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303 Data files visible to you, out of a total of 309
No description specified

Creator: Frank A. Meineke

Submitter: Frank A. Meineke

Data file type: Clinical Data

No description specified

Creator: Frank A. Meineke

Submitter: Frank A. Meineke

Data file type: Clinical Data

Risklayer Explorer is a collaboration between Risklayer GmbH and the Karlsruhe Institute of Technology's Center for Disaster Risk Management and Risk Reduction Technology (CEDM).

Creator: René Hänsel

Submitter: René Hänsel

Data file type: Geographical Data

Human Diseases: COVID-19

A dataset with information on cancer history, mutation status and surveillance history for more than 100 000 study patients is provided in i2b2 (Informatics for Integrating Biology and the Bedside, http://www.i2b2.org/software). Members of the German Consortium for Hereditary Breast and Ovarian Cancer can request access to i2b2 and will be able to perform database queries independently, e.g. with regard to identify suitable patient populations for scientific evaluation projects.

Creators: Silke Zachariae, Christoph Engel

Submitter: René Hänsel

Data file type: Clinical Data

Human Diseases: hereditary breast ovarian cancer syndrome

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: Andreas Kühnapfel

Submitter: Andreas Kühnapfel

Data file type: Not specified

No description specified

Creator: European Centre for Disease Prevention and Control

Submitter: René Hänsel

Data file type: Geographical Data

Human Diseases: COVID-19

No description specified

Creator: Johns Hopkins University

Submitter: René Hänsel

Data file type: Geographical Data

Human Diseases: COVID-19

No description specified

Creator: Robert Koch Institute

Submitter: René Hänsel

Data file type: Geographical Data

Human Diseases: COVID-19

Feature service with the current Covid-19 infections per 100,000 inhabitants on the German federal states. The service is updated daily with the current case numbers of the Robert Koch Institute.

Data source: Robert Koch Institute
Terms of Use: Robert Koch Institute; German Federal Agency for Cartography and Geodesy
Source note: Robert Koch-Institute (RKI), dl-en/by-2-0 Disclaimer: "The content made available on the Internet pages of the Robert Koch-Institute is intended solely for the general
...

Creator: Robert Koch Institute

Submitter: René Hänsel

Data file type: Not specified

Human Diseases: COVID-19

Feature service with the current Covid-19 infections per 100,000 inhabitants on the German districts. The service is updated daily with the current case numbers of the Robert Koch Institute.

Data source: Robert Koch Institute
Terms of Use: Robert Koch Institute; German Federal Agency for Cartography and Geodesy
Source note: Robert Koch-Institute (RKI), dl-en/by-2-0 Disclaimer: "The content made available on the Internet pages of the Robert Koch-Institute is intended solely for the general information
...

Creator: Robert Koch Institute

Submitter: René Hänsel

Data file type: Not specified

Human Diseases: COVID-19

T2DM Phenotype Algorithm Specification Ontology (PASO) developed using PhenoMan

The tabular representation of the T2DM phenotype algorithm generated by PhenoMan using the T2DM ontology

Based on the assumption that molecular mechanisms involved in cancerogenesis are characterized by groups of coordinately expressed genes, we developed and validated a novel method for analyzing transcriptional data called Correlated Gene Set Analysis (CGSA). Using 50 extracted gene sets we identified three different profiles of tumors in a cohort of 364 Diffuse large B-cell (DLBCL) and related mature aggressive B-cell lymphomas other than Burkitt lymphoma. The first profile had high level of
...

Creator: Maciej Rosolowski

Submitter: Christoph Beger

Data file type: Transcriptomic Data

Human Diseases: diffuse large B-cell lymphoma

307 single cells cultured from three biopsies of three different patients with a BRAF/NRAS wild type, BRAF mutant/NRAS wild type and BRAF wild type/NRAS mutant melanoma metastasis, respectively

Creators: Henry Löffler-Wirth, Hans Binder, Manfred Kunz

Submitter: Christoph Beger

Data file type: Genomic Data

Human Diseases: melanoma

Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed Methylation profiling of primary tumor samples from 122 patients with cerebral gliomas with WHO grade II and grade III tumors.

Creators: Henry Löffler-Wirth, Hans Binder, Markus Kreuz

Submitter: Christoph Beger

Data file type: Methylation Data

Human Diseases: brain glioma

Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed Methylation profiling of primary tumor samples from 122 patients with cerebral gliomas with WHO grade II and grade III tumors.

Creators: Henry Löffler-Wirth, Hans Binder, Markus Kreuz

Submitter: Christoph Beger

Data file type: Methylation Data

Human Diseases: brain glioma

Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed microarray-based genome- and transcriptome-wide molecular profiling of primary tumor samples from 137 patients with cerebral gliomas, 61 WHO grade II and 76 WHO grade III tumors.

Creators: Henry Löffler-Wirth, Markus Kreuz

Submitter: Christoph Beger

Data file type: Genomic Data

Human Diseases: brain glioma

We performed gene-expression profiling using Affymetrix U133A GeneChips with RNA from 220 mature aggressive B-cell lymphomas, including a core group of 8 Burkitt's lymphomas that met all World Health Organization (WHO) criteria. A molecular signature for Burkitt's lymphoma was generated, and chromosomal abnormalities were detected with interphase fluorescence in situ hybridization and array-based comparative genomic hybridization.

Creator: Michael Hummel

Submitter: Christoph Beger

Data file type: Genomic Data

Human Diseases: B-cell lymphoma

SNP summary statistics for three PWV modes (baPWV, cfPWV, bfPWV) - all samples. Adjusted for sex, age, log(SYS).

Creator: Michael Rode

Submitter: Michael Rode

Data file type: Not specified

This data file contains FHIR bundles of observation resources, which were used for the evaluation of the PhenoMan.
Originally the observation data were generated with Synthea(TM) and truncated to reduce overall size and import times into a HAPI FHIR JPA Server.
Please import the patient resources prior to the observations.

This data file contains 8,026,380 observations.

This data file contains FHIR bundles of patient resources, which were used for the evaluation of the PhenoMan.
Originally the patient data were generated with Synthea(TM) and truncated to reduce overall size and import times into a HAPI FHIR JPA Server.

This data file contains 66,018 patients.

This data file contains FHIR bundles of allergy intolerance resources, which were used for the evaluation of the PhenoMan.
Originally the allergy intolerance data were generated with Synthea(TM) and truncated to reduce overall size and import times into a HAPI FHIR JPA Server.
Please import the patient resources prior to the allergy intolerances.

This data file contains 563 allergy intolerances.

This data file contains FHIR bundles of condition resources, which were used for the evaluation of the PhenoMan.
Originally the condition data were generated with Synthea(TM) and truncated to reduce overall size and import times into a HAPI FHIR JPA Server.
Please import the patient resources prior to the conditions.

This data file contains 139,763 conditions.

No description specified

Creator: Matthias Löbe

Submitter: Christoph Beger

Data file type: Not specified

Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed microarray-based genome- and transcriptome-wide molecular profiling of primary tumor samples from 137 patients with cerebral gliomas, 61 WHO grade II and 76 WHO grade III tumors.

Creators: Henry Löffler-Wirth, Hans Binder

Submitter: Henry Löffler-Wirth

Data file type: SOM Data

Human Diseases: brain glioma

Data for visualisation of associations and causal relationsships of SNPs, gene expression, and metabolites based on 1,856 individuals of the LIFE Heart study

Creator: Markus Scholz

Submitter: Christoph Beger

Data file type: Other OMICs Data

Human Diseases: kidney disease

No description specified

Creator: Markus Scholz

Submitter: Christoph Beger

Data file type: Clinical Data

Summary statistics from GWAS of CPS_mean for
- all samples (adjusted for age and sex)
- men only (adjusted for age)
- women only (adjusted for age)

These data are intended for research purposes only.

Citation:
Pott et al. (2020) Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. PLOS ONE. PubMed ID: 32469969

When using this data acknowledge the source as follows: 'Data on mean degree of stenosis has been contributed by LIFE-Adult investigators and has been downloaded
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Not specified

Summary statistics from GWAS of CPS_sum for
- all samples (adjusted for age and sex)
- men only (adjusted for age)
- women only (adjusted for age)

These data are intended for research purposes only.

Citation:
Pott et al. (2020) Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. PLOS ONE. PubMed ID: 32469969

When using this data acknowledge the source as follows: 'Data on sum of stenosis has been contributed by LIFE-Adult investigators and has been downloaded from
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Not specified

Summary statistics from GWAS of CPS_max for
- all samples (adjusted for age and sex)
- men only (adjusted for age)
- women only (adjusted for age)

These data are intended for research purposes only.

Citation:
Pott et al. (2020) Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. PLOS ONE. PubMed ID: 32469969

When using this data acknowledge the source as follows: 'Data on maximal degree of stenosis has been contributed by LIFE-Adult investigators and has been downloaded
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Not specified

Summary statistics from GWAS of CPA_mean for
- all samples (adjusted for age and sex)
- men only (adjusted for age)
- women only (adjusted for age)

These data are intended for research purposes only.

Citation:
Pott et al. (2020) Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. PLOS ONE. PubMed ID: 32469969

When using this data acknowledge the source as follows: 'Data on mean area of detected plaques has been contributed by LIFE-Adult investigators and has been downloaded
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Not specified

Summary statistics from GWAS of CPA_sum for
- all samples (adjusted for age and sex)
- men only (adjusted for age)
- women only (adjusted for age)

These data are intended for research purposes only.

Citation:
Pott et al. (2020) Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. PLOS ONE. PubMed ID: 32469969

When using this data acknowledge the source as follows: 'Data on sum of plaque areas has been contributed by LIFE-Adult investigators and has been downloaded from
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Not specified

Summary statistics from GWAS of CPA_max for
- all samples (adjusted for age and sex)
- men only (adjusted for age)
- women only (adjusted for age)

These data are intended for research purposes only.

Citation:
Pott et al. (2020) Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. PLOS ONE. PubMed ID: 32469969

When using this data acknowledge the source as follows: 'Data on area of the largest plaque detected has been contributed by LIFE-Adult investigators and has been
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Not specified

No description specified

A series of 80 samples from benign melanocytic nevi and primary melanoma samples were analyzed by RNA sequencing (RNA-seq) to identify transcriptomic changes underlying early melanoma development.

Creator: Henry Löffler-Wirth

Submitter: Henry Löffler-Wirth

Data file type: Other OMICs Data

Progression free survival and overall survival of patients with brain tumors dependent on IDH1 mutation, methyltransferase (MGMT) methylation, age, WHO diagnosis and combinations of these factors.

Creator: Bettina Hentschel

Submitter: Christoph Beger

Data file type: Clinical Data

Human Diseases: brain glioma, brain glioblastoma multiforme

Example Reasoner Report generated by PhenoMan

Example Reasoner Report generated by PhenoMan

Example Reasoner Report generated by PhenoMan

Example Reasoner Report generated by PhenoMan

Example Reasoner Report generated by PhenoMan

The decision tree was generated by PhenoMan in GraphML format and was processed using an automatic layout of the yEd Graph Editor. Nonetheless, it is also possible to generate the complete tree as image in PNG format.

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: Clinical Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: Clinical Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: Clinical Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: Clinical Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: Clinical Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: Clinical Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: Clinical Data

Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: Clinical Data

Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: Clinical Data

OBJECTIVES: Although patients with depression often suffer from sleep disturbances, most of them are not sleepy. Upregulation of brain arousal has been proposed as pathophysiological mechanism explaining sleep disturbances, inner tension, autonomic hyperarousal and anhedonia in depression. The aim of the current study was to examine the association between night-time sleep disturbances and brain arousal regulation the next day in depressed versus non-depressed subjects. METHODS: Twenty-eight
...

Creator: Christian Sander

Submitter: René Hänsel

Data file type: Not specified

Summary statistics from meta GWAS of cortisol for
- all samples (adjusted for age, log(BMI) and sex)
- men only (adjusted for age and log(BMI))
- women only (adjusted for age and log(BMI))

These data are intended for research purposes only.

Citation:
Pott et al. (2019) Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease. J Clin Endocrinol Metab 104: 5008–5023. PubMed ID: 31169883

When using this data acknowledge the source as
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Other OMICs Data

Summary statistics from meta GWAS of DHEAS for
- all samples (adjusted for age, log(BMI) and sex)
- men only (adjusted for age and log(BMI))
- women only (adjusted for age and log(BMI))

These data are intended for research purposes only.

Citation:
Pott et al. (2019) Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease. J Clin Endocrinol Metab 104: 5008–5023. PubMed ID: 31169883

When using this data acknowledge the source as follows:
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Other OMICs Data

Summary statistics from meta GWAS of testosterone for
- all samples (adjusted for age, log(BMI) and sex)
- men only (adjusted for age and log(BMI))
- women only (adjusted for age and log(BMI))

These data are intended for research purposes only.

Citation:
Pott et al. (2019) Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease. J Clin Endocrinol Metab 104: 5008–5023. PubMed ID: 31169883

When using this data acknowledge the source as
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Other OMICs Data

Summary statistics from meta GWAS of estradiol for
- all samples (adjusted for age, log(BMI) and sex)
- men only (adjusted for age and log(BMI))
- women only (adjusted for age and log(BMI))

These data are intended for research purposes only.

Citation:
Pott et al. (2019) Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease. J Clin Endocrinol Metab 104: 5008–5023. PubMed ID: 31169883

When using this data acknowledge the source as
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Other OMICs Data

Summary statistics from meta GWAS of progesterone for
- all samples (adjusted for age, log(BMI) and sex)
- men only (adjusted for age and log(BMI))
- women only (adjusted for age and log(BMI))

These data are intended for research purposes only.

Citation:
Pott et al. (2019) Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease. J Clin Endocrinol Metab 104: 5008–5023. PubMed ID: 31169883

When using this data acknowledge the source as
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Other OMICs Data

Summary statistics from meta GWAS of aldosterone for
- all samples (adjusted for age, log(BMI) and sex)
- men only (adjusted for age and log(BMI))
- women only (adjusted for age and log(BMI))

These data are intended for research purposes only.

Citation:
Pott et al. (2019) Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease. J Clin Endocrinol Metab 104: 5008–5023. PubMed ID: 31169883

When using this data acknowledge the source as
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Other OMICs Data

Summary statistics from meta GWAS of 17-OH-progesterone for
- all samples (adjusted for age, log(BMI) and sex)
- men only (adjusted for age and log(BMI))
- women only (adjusted for age and log(BMI))

These data are intended for research purposes only.

Citation:
Pott et al. (2019) Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease. J Clin Endocrinol Metab 104: 5008–5023. PubMed ID: 31169883

When using this data acknowledge the source
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Other OMICs Data

Summary statistics from meta GWAS of androstenedione for
- all samples (adjusted for age, log(BMI) and sex)
- men only (adjusted for age and log(BMI))
- women only (adjusted for age and log(BMI))

These data are intended for research purposes only.

Citation:
Pott et al. (2019) Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease. J Clin Endocrinol Metab 104: 5008–5023. PubMed ID: 31169883

When using this data acknowledge the source
...

Creator: Janne Pott

Submitter: Janne Pott

Data file type: Other OMICs Data

The goal of this study was to investigate to what extent body mass index (BMI), body height, body
weight, breast-to-abdomen-ratio, testosterone, estradiol, dehydroepiandrosterone-sulfate (DHEA-S), folliclestimulating hormone, and luteinizing hormone are associated with the sound pressure level and the fundamental frequency of the speaking voice in a cross-sectional approach among adults in the general population.

Data for Publication: Jost L, et al; J Voice. 2017 Jul 21. pii: S0892-1997(17)30216-3.
...

Creators: Christoph Engel, Christoph Engel

Submitter: René Hänsel

Data file type: Clinical Data

Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)

This file contains the metadata of the MInT study formatted as CDISC ODM.

Creator: Marita Ziepert

Submitter: Christoph Beger

Data file type: ODM Data

Human Diseases: non-Hodgkin lymphoma, B-cell lymphoma

Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)

MInT study result data as CIDISC ODM

Creator: Marita Ziepert

Submitter: Christoph Beger

Data file type: ODM Data

Human Diseases: non-Hodgkin lymphoma, B-cell lymphoma

Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)

Trial data as CDISC ODM file

Creator: Marita Ziepert

Submitter: Christoph Beger

Data file type: ODM Data

Human Diseases: B-cell lymphoma

Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)

Trial data as CDISC ODM file

Creator: Marita Ziepert

Submitter: Christoph Beger

Data file type: ODM Data

Human Diseases: non-Hodgkin lymphoma, B-cell lymphoma

Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)
Sample Size: 164

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Christoph Engel

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Christoph Engel

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Markus Löffler

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Markus Löffler

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Markus Löffler

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Markus Löffler

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Markus Löffler

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Markus Löffler

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Markus Löffler

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Markus Löffler

Submitter: René Hänsel

Data file type: ODM Data

Our first objective was to compare the molecular features of subgroups of HNSCC defined by their HPV16 DNA and RNA status. The second objective was to identify gene expression subtypes in HNSCC and to correlate them with other characteristics of the patients.

HPV DNA and RNA status, mutations of 50 genes, survival and other clinical characteristics of 270 patients with head and neck cancer.

Creator: Maciej Rosolowski

Submitter: René Hänsel

Data file type: ODM Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: ODM Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

Our first objective was to compare the molecular features of subgroups of HNSCC defined by their HPV16 DNA and RNA status. The second objective was to identify gene expression subtypes in HNSCC and to correlate them with other characteristics of the patients.

HPV DNA and RNA status, mutations of 50 genes, survival and other clinical characteristics of 270 patients with head and neck cancer.

Creator: Maciej Rosolowski

Submitter: René Hänsel

Data file type: Clinical Data

Our first objective was to compare the molecular features of subgroups of HNSCC defined by their HPV16 DNA and RNA status. The second objective was to identify gene expression subtypes in HNSCC and to correlate them with other characteristics of the patients.

HPV DNA and RNA status, mutations of 50 genes, survival and other clinical characteristics of 270 patients with head and neck cancer.

Creator: Maciej Rosolowski

Submitter: René Hänsel

Data file type: Clinical Data

Our first objective was to compare the molecular features of subgroups of HNSCC defined by their HPV16 DNA and RNA status. The second objective was to identify gene expression subtypes in HNSCC and to correlate them with other characteristics of the patients.

HPV DNA and RNA status, mutations of 50 genes, survival and other clinical characteristics of 270 patients with head and neck cancer.

Creator: Maciej Rosolowski

Submitter: Christoph Beger

Data file type: Clinical Data

Human Diseases: head and neck squamous cell carcinoma

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

For a closer description, see the publication to which the file is attached.

Creators: Marcus Wagner, René Hänsel

Submitter: Marcus Wagner

Data file type: Image Data

PURPOSE: The aim of this study was to test psychometric properties of the Satisfaction with Life Scale (SWLS), to provide normative values, and to analyze associations between life satisfaction and sociodemographic and behavioral data. METHODS: A German community sample (n = 9711) with an age range of 18-80 years was surveyed using the SWLS and several other questionnaires. Confirmatory factor analysis (CFA) was used to test the dimensionality of the SWLS. Invariance across gender and age groups
...

Creator: Andreas Hinz

Submitter: René Hänsel

Data file type: Clinical Data

PURPOSE: Daytime sleepiness is associated with several medical problems. The aim of this paper is to provide normative values for one of the most often used questionnaires measuring daytime sleepiness, the Epworth Sleepiness Scale (ESS). METHODS: A large sample of 9711 people from the German general population took part in this study. In addition to the ESS, several other questionnaires were used, and sociodemographic and behavioral factors were recorded. RESULTS: Normative values for the ESS are
...

Creator: Christian Sander

Submitter: René Hänsel

Data file type: Clinical Data

Background/Objective: The Life Orientation Test-Revised (LOT-R) is often used to assess dispositional optimism. The aims of this study were to test psychometric properties of the LOT-R, to provide normative scores, and to test the association between optimism and several psychological, sociodemographic, and behavioral factors. Method: A randomly selected German general population community sample with an age range of 18-80 years (N = 9,711) was surveyed. Results: The Confirmatory Factor Analysis
...

Creator: Andreas Hinz

Submitter: René Hänsel

Data file type: Clinical Data

PURPOSE: The Sniffin' Sticks Screening 12 test is a test of olfactory performance based on pen-like odor dispensing devices. The aims of this study were to analyze the performance of this test in a general population sample and to explore associations between olfactory dysfunction and quality of life. METHODS: A large community sample (n = 7267) completed the Sniffin' Sticks Screening 12 test and several questionnaires measuring quality of life, anxiety, dispositional optimism, social support,
...

Creator: Andreas Hinz

Submitter: René Hänsel

Data file type: Clinical Data

BACKGROUND: The Generalized Anxiety Disorder Scales GAD-7 and GAD-2 are instruments for the assessment of anxiety. The aims of this study are to test psychometric properties of these questionnaires, to provide normative values, and to investigate associations with sociodemographic factors, quality of life, psychological variables, and behavioral factors. METHODS: A German community sample (n=9721) with an age range of 18-80 years was surveyed using the GAD-7 and several other questionnaires.
...

Creator: Andreas Hinz

Submitter: René Hänsel

Data file type: Clinical Data

BACKGROUND: The Pittsburgh Sleep Quality Index (PSQI) is frequently used to assess sleep problems in patients. The aim of this study was to provide reference values for this questionnaire, to test psychometric properties, and to analyze associations with psychological, sociodemographic, and behavioral factors. METHODS: A German community sample comprising 9284 adult residents (aged 18-80 years) was surveyed using the PSQI and several other questionnaires. RESULTS: According to the generally
...

Creator: Andreas Hinz

Submitter: René Hänsel

Data file type: Not specified

BACKGROUND: The PHQ-15 is widely used as an open access screening instrument for somatic symptoms in different health care settings. The objectives of the study were to contribute to the construct validity and to generate normative data for the PHQ-15. METHODS: The survey was conducted in the general population in Germany from August 2011 to November 2014 (n=9250). All participants underwent an extensive core assessment including a set of questionnaires. RESULTS: Men reported significantly less
...

Creator: Andreas Hinz

Submitter: René Hänsel

Data file type: Clinical Data

We performed gene-expression profiling using Affymetrix U133A GeneChips with RNA from 873 biopsy specimens including diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), Burkitt’s lymphoma (BL), mixed FL/DLBCL lymphomas, primary mediastinal large B-cell lymphoma (PMBL), multiple myeloma (MM), IRF4-rearranged large cell lymphoma, MYC-negative high-grade B-cell lymphomas with Chr. 11q aberration pattern (mnBLL-11q), and Mantle cell lymphoma (MCL).

Creator: Henry Löffler-Wirth

Submitter: Henry Löffler-Wirth

Data file type: Other OMICs Data

BACKGROUND:Animal experiments and studies in alcohol dependent patients indicate that ghrelin signaling in the brain is causally involved in the regulation of alcohol reward and intake. Increasing ghrelin levels enhances alcohol craving and intake, blocking ghrelin receptors abolishes these effects. If ghrelin is also involved in non-dependent alcohol consumption in humans, though, remains unknown. The aim was therefore to investigate the relationship between ghrelin serum levels and alcohol
...

Creator: Dirk Alexander Wittekind

Submitter: René Hänsel

Data file type: Clinical Data

BACKGROUND: Reference intervals for leukocyte subsets from peripheral blood are helpful for the understanding of disease states and therapy effects. METHODS: We performed in-depth immunophenotyping for 608 healthy German adults from the Leipzig region from 40 to 79 years by 10-color flow cytometry (FCM) to gain reference information for various leukocyte subsets including subsets of granulocytes, monocytes and lymphocytes. RESULTS: First, we derived gender- and age-specific reference intervals
...

Creator: Silke Zachariae

Submitter: Silke Zachariae

Data file type: Not specified

Three-dimensional (3D) whole body scanner data of nearly 10,000 participants of a cohort collected from the adult population of Leipzig.

Creator: Henry Löffler-Wirth

Submitter: Henry Löffler-Wirth

Data file type: Not specified

trial data for the mental demandVariableMeaning Gender0=female1=maleMarital Status0 = married, living with partner1 = married and living separated, single, divorced, widowedEducation1 = low2 = medium3 = highEver_diabetes/ heart attack0 = no1 = yesDepression0 = no1 = yes

Creator: Christoph Engel

Submitter: René Hänsel

Data file type: Not specified

No description specified

Creator: Silke Zachariae

Submitter: Silke Zachariae

Data file type: Not specified

Recent technological advances in single-cell genomics make it possible to analyze cellular heterogeneity of tumor samples. Here, we applied single-cell RNA-seq to measure the transcriptomes of 307 single cells cultured from three biopsies of three different patients with a BRAF/NRAS wild type, BRAF mutant/NRAS wild type and BRAF wild type/NRAS mutant melanoma metastasis, respectively. Analysis based on self-organizing maps identified sub-populations defined by multiple gene expression modules
...

Creator: Henry Löffler-Wirth

Submitters: René Hänsel, Henry Löffler-Wirth

Data file type: SOM Data

Cognitive assessments comprised tests from the Consortium to Establish a Registry for Alzheimer's Disease (CERAD): verbal fluency (VF), word list learning and recall (WLL, WLR), and the Trail Making Tests (TMT) A and B. The "Sniffin' Sticks Screening 12" test was used to measure olfactory performance. Linear regression analyses were performed to determine associations between the number of correctly identified odors (0 to 12) and the five cognitive test scores, adjusted for sex, age, education,
...

Creator: Christoph Engel

Submitter: René Hänsel

Data file type: Clinical Data

A total of 2695 individuals (age 40-79 years, 48% men) without prior diagnosis of diabetes and complete measurement of HbA1c, FPG, 2 h-PG and urine albumin-creatinine ratio (UACR) were taken from a large population-based epidemiological study in the City of Leipzig, Germany.

Diabetes screening strategies using glycated haemoglobin (HbA1c) as first-instance diagnostic parameter may cause failure to detect individuals with abnormal glucose regulation and possible signs of microvascular complications
...

Creator: Christoph Engel

Submitter: René Hänsel

Data file type: Clinical Data

Single-cell transcriptomics has been used for analysis of heterogeneous populations of cells during developmental processes and for analysis of tumor cell heterogeneity. More recently, analysis of pseudotime (PT) dynamics of heterogeneous cell populations has been established as a powerful concept to study developmental processes. Here we perform PT analysis of 3 melanoma short-term cultures with different genetic backgrounds to study specific and concordant properties of PT dynamics of selected
...

Creator: Henry Löffler-Wirth

Submitters: René Hänsel, Henry Löffler-Wirth

Data file type: SOM Data

For this study, we screened prospectively recruited patients with a histopathological reference diagnosis of cerebral tumors of WHO grade II and III, known KPS at diagnosis, information on extent of resection by early postoperative neuroimaging, available frozen tissue specimens from the initial operation, and documented clinical outcome.

Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological
...

Creator: Henry Löffler-Wirth

Submitters: René Hänsel, Henry Löffler-Wirth

Data file type: SOM Data

ROIs of size 600 x 900 px (0.109 mm^2) size were chosen from 25 expert-specified tumor subregions within DLBCL biopsy specimens. Images were generated by Hamamatsu Nanozoomer 2.0 RS slide scanner. ROI no. 1 - 25 represent staining with CD14 antibody (imaged at 488 nm wavelength), ROI no. 26 -- 50 represent staining with CD163 antibody (imaged at 555 nm wavelength). Imaged regions in ROIs no. 1 and 26, 2 and 27, ... , coincide. Data were used for mutual comparison of automated macrophage recognition
...

Creators: Marcus Wagner, René Hänsel

Submitter: René Hänsel

Data file type: Image Data