Projects

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35 Projects found

B-cell lymphoma is the most frequent lymphoid neoplasia accounting for one third of all lymphomas. R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone) is the current treatment standard, leading to high cure rates especially in younger patients. Although the 3-year event-free survival is about 60% even for elderly patients between 60-80 years old, the remainder of patients eventually relapse and the majority die of their disease. The German Non-Hodgkin's Lymphoma Study
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Programme: NHL

Public web page: https://www.dshnhl.org

The group is interested in omic-level studies including the genome, methylome, transcriptome, and metabolome of the general population as well as of various diseases including cardiovascular diseases, pneumonia, sepsis, obesity, and brain cancers. Additionally, we aim at transfering results of biomathematical model simulations into clinical practice e.g. by haematopoietic growth-factor opimization during cytotoxic chemotherapy and optimization of EPO applications in chronic kidney disease.

The
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Programme: This Project is not associated with a Programme

Public web page: http://www.imise.uni-leipzig.de/en/Groups/GenStat/

Start date: 1st Jan 2013

The aim of the Head and Neck Group within the Leipzig Research Center for Civilization Diseases (LIFE) is to facilitate improvements in the treatment and care of head and neck cancer patients through insights from molecular studies.

The Head and Neck Group within the Leipzig Research Center for Civilization Diseases (LIFE) investigates the molecular mechanisms and the diagnostic and prognostic factors of head and neck cancer. For this purpose, we collected phenotypic information from about 300
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Programme: This Project is not associated with a Programme

Public web page: http://life.uni-leipzig.de/

Start date: 1st Jan 2012

End date: 31st Dec 2012

Historic retinal images of subjects with diabetes are scanned and analysed using modern technology. The accuracy of the methods and the usefulness of the findings in the long-term are in the focus. University of Oulu, Department of Ophthalmology/PEDEGO Research Unit 194/2006

Programme: This Project is not associated with a Programme

Public web page: https://www.oulu.fi/mrc/research-groups/falck-hautala

Project for testing requests and functions of LHA

Programme: This Project is not associated with a Programme

Public web page: Not specified

Start date: 31st Mar 2021

The aim of this project is to validate and improve an in vitro test system developed in a previous project for the prediction of hepatotoxicity induced by chemical substances and drugs. For this purpose, the test system will be supplemented with immunological cells in order to be able to detect idiosyncratic reactions. In the subproject of the working group of Prof. Daniel Seehofer and Dr. Georg Damm, primary liver cells will be provided and the in vitro model will be improved by Kupffer cells.

Programme: This Project is not associated with a Programme

Public web page: Not specified

Start date: 1st Feb 2017

End date: 31st Dec 2020

This population-based study examined 10,000 participants randomly selected from the Leipzig population (2011 to 2014). A follow-up is to be carried out from 2017 - 2020. The study mainly included people aged between 40 and 79. All participants underwent a 6-hour study program and people over 60 years of age were invited two more times to in-depth study of cognition and depression and the brain (MRI, EEG). Extensive measurements of genome, metabolome and transcriptome are available. The LIFE-ADULT
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Programme: Epidemiology

Public web page: http://life.uni-leipzig.de/en/adults/life_adult.html

Start date: 1st Jan 2009

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