Studies

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26 Studies visible to you, out of a total of 26

We analysed if measuring PWV in different segments of the body leads to association with different genetic variants, as well as different heritability and different genetic correlation with other biological traits. Furthermore we searched for shared genetic architecture concerning PWV, blood pressure (BP) and coronary artery disease (CAD) and examined the causal relationship between PWV and BP.

Person responsible: Janne Pott

Snapshots: No snapshots

Study type: Genetic study

We evaluated if the PhenoMan returns correct/complete result sets and if it is working with real data. To simulate a FHIR health data store with real data we used Synthea(TM) to generate a large data set and imported it into a HAPI FHIR JPA Server. Based on the synthetic data set we developed ten example queries with different structure and complexity with PhenoMan and SQL. We compared the results of the queries in means of execution time and equality of results.

The detailed steps of the evaluation
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Person responsible: Christoph Beger

Snapshots: No snapshots

Study type: Not specified

No description specified

Person responsible: Alexandr Uciteli

Snapshots: No snapshots

Study type: Not specified

We defined six operationalizations of CPB considering plaques in common carotid arteries, carotid bulb, and internal carotid arteries (maximal plaque area, mean plaque area, sum of plaque areas at all six regions, maximal degree of stenosis, mean degree of stenosis, and sum of stenosis at all six regions).
Link to publication (PMID, DOI), Supplemental Figures and Tables, and Summary Statistics of GWAS will be made available upon acceptance of our manuscript.

Person responsible: Janne Pott

Snapshots: No snapshots

Study type: Genetic study

Supplement Data for Publication including Supplement Material & Results (eQTL annotation, Mendelian Randomization (MR), further significant loci), Figures (correlation plot of steroid hormones, scatter plot of genetic effect sizes, regional association plots, scatter plots of MR) and Tables (Correlations, GWAS summary statistics, interaction tests, MR results)

Person responsible: Janne Pott

Snapshots: No snapshots

Study type: Genetic study

No description specified

Person responsible: Alexandr Uciteli

Snapshots: No snapshots

Study type: Not specified

Stratification of head and neck squamous cell carcinomas (HNSCC) based on HPV16 DNA and RNA status

Person responsible: Maciej Rosolowski

Snapshots: No snapshots

Study type: Clinical study (Phase 1)

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