Projects

Leipzig Human Glands project consists of studies of the Institute of the Veterinary Physiology (Leipzig University) and the Interdisciplinary Center for Bioinformatics (IZBI, Leipzig University). Spatially resolved transcriptome analyses of human glands (sebaceous gland, meibomian gland) where preformed in the frame of this undertaking.

The Systems Medicine of Mitochondrial Parkinson’s Disease (SysMedPD) study was initiated by an international consortium to contribute to the elucidation of mitochondrial underpinnings of Parkinson's Disease (PD).

Project for testing requests and functions of LHA

The cultivated grape (Vitis vinifera) has become the world’s leading fruit crop. Grape is unique not only because it is a major global perennial crop but also for its historical and cultural connections with the development of humans. One of the main challenges for viticulture is to sustainably maintain the production of high-quality grape varieties in the face of climate change. Current models predict an increasing disease pressure for grapes, mainly because of warmer and partly drier conditions. ...

Background Single-cell RNA sequencing (scRNAseq) has been widely applied to dissect cellular heterogeneity in normal and diseased skin. Sebaceous glands, essential skin components with established functions in maintaining skin integrity and emerging roles in systemic energy metabolism, have been largely neglected in scRNAseq studies. Methods Departing from mouse and human skin scRNAseq datasets, we identified gene sets expressed especially in sebaceous glands with the open-source R-package oposSOM. ...