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- Markus Löffler
Prof. Dr. Markus Löffler
Universität Leipzig
Institut für Medizinische Informatik, Statistik und Epidemiologie
Härtelstraße 16-18
04107 Leipzig
Health Atlas ID: 7W2GKE4JDQ-2
Location:
Germany
Expertise: Not specified
Tools: Not specified
ORCID: Not specified

Project roles
Pal
- LIFE HNC - Head and Neck Cancer Group
- MMML-MYC-SYS
- LIFE Adult
- GLA - German Lymphoma Alliance
- MMML - Molecular mechanisms in malignant lymphoma
- MMML Demonstrators - Molecular Mechanisms in Malignant Lymphomas - Demonstrators of Personalized Medicine
- HaematoSys - Systems biology of haematopoiesis and haematopoietic neoplasia
- SMITH - Smart Medical Information Technology for Healthcare
- LHA - Leipzig Health Atlas

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MMML Demonstrators - Molecular Mechanisms in Malignant Lymphomas - Demonstrators of Personalized Medicine (Institute for Medical Informatics, Statistics and Epidemiology) ; LIFE HNC - Head and Neck Cancer Group (Institute for Medical Informatics, Statistics and Epidemiology) ; MMML-MYC-SYS (Institute for Medical Informatics, Statistics and Epidemiology) ; LIFE Adult (Institute for Medical Informatics, Statistics and Epidemiology) ; GLA - German Lymphoma Alliance (Institute for Medical Informatics, Statistics and Epidemiology) ; MMML - Molecular mechanisms in malignant lymphoma (Institute for Medical Informatics, Statistics and Epidemiology) ; SepNet - German Competence Network Sepsis (Institute for Medical Informatics, Statistics and Epidemiology) ; HaematoSys - Systems biology of haematopoiesis and haematopoietic neoplasia (Institute for Medical Informatics, Statistics and Epidemiology) ; SMITH - Smart Medical Information Technology for Healthcare (Institute for Medical Informatics, Statistics and Epidemiology) ; LHA - Leipzig Health Atlas (Institute for Medical Informatics, Statistics and Epidemiology) ; POLAR - Polypharmacy, Drug Interactions, Risks (Institute for Medical Informatics, Statistics and Epidemiology) ; SMITH - Smart Medical Information Technology for Healthcare (University of Leipzig) ; COVID-19 Leipzig (Institute for Medical Informatics, Statistics and Epidemiology)
Related items
- Projects (13)
- Institutions (2)
- Investigations (1)
- Studies (1)
- Resources (2)
- Publications (182)
- Data files (20+2)
- Documents (12)
This project serves as a container for all COVID-19 related assets, developed at the University of Leipzig and its partners.
Organisms: Homo sapiens, Severe acute respiratory syndrome coronavirus 2
Human Diseases: COVID-19
Programme: MII - Medical Informatics Initiative
Public web page: https://www.smith.care/
Start date: 1st Jan 2018
Organisms: Homo sapiens
The Leipzig Health Atlas (LHA) is an alliance of medical ontologists, medical systems biologists and clinical trials groups to design and implement a multi-functional and quality-assured atlas. It provides models, data and metadata on specific use cases from medical research fields in which our team has scientific and clinical expertise.
Programme: This Project is not associated with a Programme
Public web page: https://www.health-atlas.de
Start date: 1st Apr 2016
End date: 28th Feb 2021
Organisms: Homo sapiens
The aim of the project is to use methods and processes of the Medical Informatics Initiative (MII) to contribute to the detection of health risks in patients with polypharmacy. Polypharmacy occurs especially in elderly patients with multimorbidity. Polypharmacy associated with an increased risk for medication errors and drug-drug or drug-disease interactions, which either reduce or intensify the desired effect of individual active substances or lead to undesired adverse drug effects (ADE). In the
...
Programme: MII - Medical Informatics Initiative
Public web page: https://www.medizininformatik-initiative.de/en/POLAR
Organisms: Homo sapiens
The aim of the Head and Neck Group within the Leipzig Research Center for Civilization Diseases (LIFE) is to facilitate improvements in the treatment and care of head and neck cancer patients through insights from molecular studies.
The Head and Neck Group within the Leipzig Research Center for Civilization Diseases (LIFE) investigates the molecular mechanisms and the diagnostic and prognostic factors of head and neck cancer. For this purpose, we collected phenotypic information from about 300
...
Programme: This Project is not associated with a Programme
Public web page: http://life.uni-leipzig.de/
Start date: 1st Jan 2012
End date: 31st Dec 2012
Organisms: Homo sapiens
Human Diseases: head and neck cancer
Severe sepsis and septic shock have a high mortality. Research has concentrated on adjunctive sepsis therapies; the role of supportive measures is comparatively unclear. In Europe the use of colloids is widespread, but there is no evidence on the role of either crystalloid or colloid volume therapy in sepsis. Recently, a higher incidence of kidney failure in sepsis was reported after administration of colloids.
Snapshots: No snapshots
Studies: VISEP
Resources: VISEP metadata, VISEP trial data
Baseline Data and Endpoints for VISEP
Investigation: Efficacy of Volume Substitution and Insulin The...
Resources: VISEP metadata, VISEP trial data
The role of intensive insulin therapy in patients with severe sepsis is uncertain. Fluid resuscitation improves survival among patients with septic shock, but evidence is lacking to support the choice of either crystalloids or colloids. We compared intensive insulin therapy with conventional insulin therapy and HES with Ringer’s lactate.
Submitter: René Hänsel
Resource type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
Investigation: Efficacy of Volume Substitution and Insulin The...
Study: VISEP
Organisms: No organisms
Human Diseases: disease by infectious agent
SOPs: No SOPs
Data files: VISEP Endpoint, VISEP Endpoint-ODM, VISEP Endpoint-SPSS, VISEP V-PAT, VISEP V-PAT-ODM, VISEP V-PAT-SPSS, VISEP V-VERL-join, VISEP V-VERL-join-ODM, VISEP V-VERL-join-SPSS, VISEP haemo_join, VISEP haemo_join-ODM, VISEP haemo_join-SPSS
The role of intensive insulin therapy in patients with severe sepsis is uncertain. Fluid resuscitation improves survival among patients with septic shock, but evidence is lacking to support the choice of either crystalloids or colloids. We compared intensive insulin therapy with conventional insulin therapy and HES with Ringer’s lactate.
Submitter: René Hänsel
Resource type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
Investigation: Efficacy of Volume Substitution and Insulin The...
Study: VISEP
Organisms: No organisms
Human Diseases: disease by infectious agent
SOPs: No SOPs
Data files: VISEP Endpoint Metadata, VISEP Endpoint Metadata-ODM, VISEP V-PAT Metadata, VISEP V-PAT Metadata-ODM, VISEP V-VERL-join Metadata, VISEP V-VERL-join Metadata-ODM, VISEP haemo_join Metadata, VISEP haemo_join Metadata-ODM
Abstract (Expand)
Authors: Maciej Rosolowski, Volker Oberle, Peter Ahnert, Petra Creutz, Martin Witzenrath, Michael Kiehntopf, Markus Loeffler, Norbert Suttorp, Markus Scholz
Date Published: 1st Dec 2020
Publication Type: Journal article
Abstract (Expand)
Authors: Katja Hoffmann, Katja Cazemier, Christoph Baldow, Silvio Schuster, Yuri Kheifetz, Sibylle Schirm, Matthias Horn, Thomas Ernst, Constanze Volgmann, Christian Thiede, Andreas Hochhaus, Martin Bornhäuser, Meinolf Suttorp, Markus Scholz, Ingmar Glauche, Markus Loeffler, Ingo Roeder
Date Published: 1st Dec 2020
Publication Type: Journal article
Abstract (Expand)
Authors: F. Beyer, R. Zhang, M. Scholz, K. Wirkner, M. Loeffler, M. Stumvoll, A. Villringer, A. V. Witte
Date Published: 25th Oct 2020
Publication Type: Journal article
PubMed ID: 33100325
Citation: Int J Obes (Lond). 2020 Oct 25. pii: 10.1038/s41366-020-00702-4. doi: 10.1038/s41366-020-00702-4.
Abstract (Expand)
Authors: E. Hofer, G. V. Roshchupkin, H. H. H. Adams, M. J. Knol, H. Lin, S. Li, H. Zare, S. Ahmad, N. J. Armstrong, C. L. Satizabal, M. Bernard, J. C. Bis, N. A. Gillespie, M. Luciano, A. Mishra, M. Scholz, A. Teumer, R. Xia, X. Jian, T. H. Mosley, Y. Saba, L. Pirpamer, S. Seiler, J. T. Becker, O. Carmichael, J. I. Rotter, B. M. Psaty, O. L. Lopez, N. Amin, S. J. van der Lee, Q. Yang, J. J. Himali, P. Maillard, A. S. Beiser, C. DeCarli, S. Karama, L. Lewis, M. Harris, M. E. Bastin, I. J. Deary, A. Veronica Witte, F. Beyer, M. Loeffler, K. A. Mather, P. R. Schofield, A. Thalamuthu, J. B. Kwok, M. J. Wright, D. Ames, J. Trollor, J. Jiang, H. Brodaty, W. Wen, M. W. Vernooij, A. Hofman, A. G. Uitterlinden, W. J. Niessen, K. Wittfeld, R. Bulow, U. Volker, Z. Pausova, G. Bruce Pike, S. Maingault, F. Crivello, C. Tzourio, P. Amouyel, B. Mazoyer, M. C. Neale, C. E. Franz, M. J. Lyons, M. S. Panizzon, O. A. Andreassen, A. M. Dale, M. Logue, K. L. Grasby, N. Jahanshad, J. N. Painter, L. Colodro-Conde, J. Bralten, D. P. Hibar, P. A. Lind, F. Pizzagalli, J. L. Stein, P. M. Thompson, S. E. Medland, P. S. Sachdev, W. S. Kremen, J. M. Wardlaw, A. Villringer, C. M. van Duijn, H. J. Grabe, W. T. Jr Longstreth, M. Fornage, T. Paus, S. Debette, M. Arfan Ikram, H. Schmidt, R. Schmidt, S. Seshadri
Date Published: 22nd Sep 2020
Publication Type: Journal article
PubMed ID: 32963231
Citation: Nat Commun. 2020 Sep 22;11(1):4796. doi: 10.1038/s41467-020-18367-y.
Abstract (Expand)
Authors: Anke Toenjes, Annett Hoffmann, Susan Kralisch, Abdul Rashid Qureshi, Nora Klöting, Markus Scholz, Dorit Schleinitz, Anette Bachmann, Juergen Kratzsch, Marcin Nowicki, Sabine Paeschke, Kerstin Wirkner, Cornelia Enzenbach, Ronny Baber, Joachim Beige, Matthias Anders, Ingolf Bast, Matthias Blüher, Peter Kovacs, Markus Löffler, Ming-Zhi Zhang, Raymond C. Harris, Peter Stenvinkel, Michael Stumvoll, Mathias Fasshauer, Thomas Ebert
Date Published: 1st Sep 2020
Publication Type: Journal article
PubMed ID: 32508317
DOI: 10.1530/EJE-20-0087
Citation: European Journal of Endocrinology 183(3):233-244
Investigations: Efficacy of Volume Substitution and Insulin The...
Studies: VISEP
Resources: VISEP trial data
Investigations: Efficacy of Volume Substitution and Insulin The...
Studies: VISEP
Resources: VISEP trial data
Investigations: Efficacy of Volume Substitution and Insulin The...
Studies: VISEP
Resources: VISEP trial data
Investigations: Efficacy of Volume Substitution and Insulin The...
Studies: VISEP
Resources: VISEP trial data
Investigations: Efficacy of Volume Substitution and Insulin The...
Studies: VISEP
Resources: VISEP metadata
Summary of the current COVID-19 pandemic development in Leipzig and Saxony.
Creators: Markus Löffler, Markus Scholz, Peter Ahnert, Matthias Horn, Yuri Kheifetz, Holger Kirsten, Kolja Nenoff, Sibylle Schirm
Submitter: Christoph Beger
Investigations: No Investigations
Studies: No Studies
Resources: No Resources
Summary of the current COVID-19 pandemic development in Leipzig and Saxony.
Creators: Markus Scholz, Markus Löffler, Peter Ahnert, Matthias Horn, Yuri Kheifetz, Holger Kirsten, Kolja Nenoff, Sibylle Schirm
Submitter: Christoph Beger
Investigations: No Investigations
Studies: No Studies
Resources: No Resources
Summary of the current COVID-19 pandemic development in Leipzig and Saxony.
Creators: Markus Löffler, Markus Scholz, Peter Ahnert, Matthias Horn, Yuri Kheifetz, Holger Kirsten, Kolja Nenoff, Sibylle Schirm
Submitter: Christoph Beger
Investigations: No Investigations
Studies: No Studies
Resources: No Resources
Summary of the current COVID-19 pandemic development in Leipzig and Saxony.
Creators: Markus Scholz, Markus Löffler, Peter Ahnert, Matthias Horn, Yuri Kheifetz, Holger Kirsten, Kolja Nenoff, Sibylle Schirm
Submitter: Christoph Beger
Investigations: No Investigations
Studies: No Studies
Resources: No Resources
Summary of the current COVID-19 pandemic development in Leipzig and Saxony.
Creators: Markus Scholz, Markus Löffler, Peter Ahnert, Matthias Horn, Yuri Kheifetz, Holger Kirsten, Sibylle Schirm
Submitter: Christoph Beger
Investigations: No Investigations
Studies: No Studies
Resources: No Resources