The aim is to develop new predictive models of haematopoiesis and models for two haematopoietic neoplasias, chronic myeloid leukemia and B-cell non-Hodgkin's lymphoma. The models should lead to a better understanding of the principles of tissue organization and to optimized therapy concepts.
In the interdisciplinary consortium HaematoSys partners from leading clinical haematooncological study groups, pathologists, geneticists, cell biologists as well as mathematicians, statisticians and bioinformaticians have joined forces.
Health Atlas ID: 7YJWXMPECN-1Funding codes:
Public web page: https://www.haematosys.de
Leipzig Health Atlas PALs: Markus Löffler
Project Coordinators: No Project coordinators for this Project
Project created: 25th Oct 2019
PubMed ID: 24886056
Citation: Theor Biol Med Model. 2014 May 26;11:24. doi: 10.1186/1742-4682-11-24.
Date Published: 12th Jun 2013
Publication Type: Not specified
Human Diseases: anemia
PubMed ID: 23755260
Citation: PLoS One. 2013 Jun 6;8(6):e65630. doi: 10.1371/journal.pone.0065630. Print 2013.
Projects: LHA - Leipzig Health Atlas, LIFE Adult, LIFE - Leipzig Research Center for Civilization Diseases, LIFE HNC - Head and Neck Cancer Group, LIFE Heart, MMML - Molecular mechanisms in malignant lymphoma, GLA - German Lymphoma Alliance, MMML Demonstrators - Molecular Mechanisms in Malignant Lymphomas - Demonstrators of Personalized Medicine, HaematoOpt - Individualized model-based managing of the next-cycle thrombopenia of CHOEP/CHOP treated patients based on platelets dynamics during the previous cycles, GC-HBOC - German Consortium for Hereditary Breast and Ovarian Cancer, GC-HNPCC - German Consortium for Hereditary Non-Polyposis Colorectal Cancer, MMML-MYC-SYS, NLP4CR - Natural Language Processing for Clinical Research, Genetical Statistics and Systems Biology, SepNet - German Competence Network Sepsis, LIFE Child, HNPCC-Sys - Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome, GGN - German Glioma Network, CAPSys - Footprints of Sepsis Framed Within Community Acquired Pneumonia in the Blood Transcriptome, ProstataCA, HaematoSys - Systems biology of haematopoiesis and haematopoietic neoplasia, SMITH - Smart Medical Information Technology for Healthcare, COVID-19 Leipzig, Management of health information systems, LivSys Transfer - Transfer of the LivSys in vitro system for hepatotoxicity into application, Project Test Demonstrator, CapSys - Systems Medicine of Community Acquired Pneumoniahttps://orcid.org/0000-0001-8344-0658
Projects: LHA - Leipzig Health Atlas, LIFE Adult, LIFE - Leipzig Research Center for Civilization Diseases, LIFE HNC - Head and Neck Cancer Group, MMML - Molecular mechanisms in malignant lymphoma, GLA - German Lymphoma Alliance, MMML Demonstrators - Molecular Mechanisms in Malignant Lymphomas - Demonstrators of Personalized Medicine, MMML-MYC-SYS, SepNet - German Competence Network Sepsis, HaematoSys - Systems biology of haematopoiesis and haematopoietic neoplasia, SMITH - Smart Medical Information Technology for Healthcare, COVID-19 Leipzig, POLAR - Polypharmacy, Drug Interactions, Risks
Prof. Dr. Markus Löffler Universität Leipzig Institut für Medizinische Informatik, Statistik und Epidemiologie Härtelstraße 16-18 04107 Leipzig
Taxonomy URI: http://purl.obolibrary.org/obo/DOID_707
Synonyms: B-cell lymphocytic neoplasm
Definitions: A non-Hodgkin lymphoma that has_material_basis_in B cells.
Taxonomy URI: http://purl.obolibrary.org/obo/DOID_0060060
Definitions: A lymphoma that is characterized as any kind of lymphoma except Hodgkin's lymphoma., OMIM mapping confirmed by DO. [LS].
Taxonomy URI: http://purl.obolibrary.org/obo/DOID_74
Synonyms: Hematological disease, DISEASE OF THE BLOOD AND BLOOD-FORMING ORGANS, disease of hematopoietic system, Blood dyscrasia NOS, Blood disease, blood disorder
Definitions: An immune system disease that has_material_basis_in hematopoietic cells.