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- HaematoOpt - Individualized model-based managing of the next-cycle thrombopenia of CHOEP/CHOP treated patients based on platelets dynamics during the previous cycles
The central objective of HaematoOpt project is to demonstrate that recently developed dynamic mathematical models of normal and leukemic hematopoiesis can be used to practically impact clinical decision- making
Programme: This Project is not associated with a Programme
Health Atlas ID: 7RRNQ9WC7J-9
Funding codes:- BMBF
Public web page: https://haematoopt.de/
Organisms: No Organisms specified
Human Diseases: Non-hodgkin lymphoma
Health Atlas PALs: Markus Scholz
Project Coordinators: No Project coordinators for this Project
Project created: 8th May 2019
Related items
Abstract (Expand)
Authors: Y. Kheifetz, M. Scholz
PubMed ID: 30840616
Citation: PLoS Comput Biol. 2019 Mar 6;15(3):e1006775. doi: 10.1371/journal.pcbi.1006775. eCollection 2019 Mar.
Abstract (Expand)
Authors: Y. Kheifetz, Markus Scholz, Markus Löffler
Citation:
Abstract (Expand)
Authors: M. Scholz, A. Gross, M. Loeffler
Date Published: 21st May 2010
Publication Type: Not specified
PubMed ID: 20083124
Citation: J Theor Biol. 2010 May 21;264(2):287-300. doi: 10.1016/j.jtbi.2009.12.032. Epub 2010 Jan 18.
Implementation of recently developed dynamic mathematical models of normal and leukemic hematopoiesis to practically impact clinical decision- making.
Fitting available individual patients information, prediction of next-cycle thrombopenia caused by CHOEP treatment based on the individual fits of the preceeding treatment cycles, changing next-cycle relative dosing, posponement of the next cycle, changing follow-up period, visualization of data and simulation
Creator: Markus Scholz
Submitter: René Hänsel
Model type: Not specified
Model format: R package
Environment: Not specified
Organism: Not specified
Human Disease: thrombocytopenia
Investigations: No Investigations
Studies: No Studies
Resources: No Resources
Projects: LHA - Leipzig Health Atlas, LIFE Adult, LIFE - Leipzig Research Center for Civilization Diseases, LIFE HNC - Head and Neck Cancer Group, LIFE Heart, MMML - Molecular mechanisms in malignant lymphoma, GLA - German Lymphoma Alliance, MMML Demonstrators - Molecular Mechanisms in Malignant Lymphomas - Demonstrators of Personalized Medicine, HaematoOpt - Individualized model-based managing of the next-cycle thrombopenia of CHOEP/CHOP treated patients based on platelets dynamics during the previous cycles, GC-HBOC - German Consortium for Hereditary Breast and Ovarian Cancer, GC-HNPCC - German Consortium for Hereditary Non-Polyposis Colorectal Cancer, MMML-MYC-SYS, NLP4CR - Natural Language Processing for Clinical Research, Genetical Statistics and Systems Biology, SepNet - German Competence Network Sepsis, LIFE Child, HNPCC-Sys - Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome, GGN - German Glioma Network, CAPSys - Footprints of Sepsis Framed Within Community Acquired Pneumonia in the Blood Transcriptome, ProstataCA, SMITH - Smart Medical Information Technology for Healthcare, COVID-19 Leipzig, Management of health information systems, LivSys Transfer - Transfer of the LivSys in vitro system for hepatotoxicity into application, Project Test Demonstrator
Institutions: Institute for Medical Informatics, Statistics and Epidemiology

Roles: Technician
Expertise: Data Management, Data analysis, Python, Html
Projects: LIFE Heart, LIFE - Leipzig Research Center for Civilization Diseases, HaematoOpt - Individualized model-based managing of the next-cycle thrombopenia of CHOEP/CHOP treated patients based on platelets dynamics during the previous cycles, Genetical Statistics and Systems Biology, COVID-19 Leipzig
Institutions: Institute for Medical Informatics, Statistics and Epidemiology
Markus Scholz
Scientific Speaker Institution
Institut für Medizinische Informatik, Statistik und Epidemiologie
Universität Leipzig
Härtelstraße 16-18
04107 Leipzig
Taxonomy URI: http://purl.obolibrary.org/obo/DOID_0060060
Definitions: A lymphoma that is characterized as any kind of lymphoma except Hodgkin's lymphoma., OMIM mapping confirmed by DO. [LS].