Henry Löffler-Wirth

307 single cells cultured from three biopsies of three different patients with a BRAF/NRAS wild type, BRAF mutant/NRAS wild type and BRAF wild type/NRAS mutant melanoma metastasis, respectively

Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed Methylation profiling of primary tumor samples from 122 patients with cerebral gliomas with WHO grade II and grade III tumors.

Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed Methylation profiling of primary tumor samples from 122 patients with cerebral gliomas with WHO grade II and grade III tumors.

Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed microarray-based genome- and transcriptome-wide molecular profiling of primary tumor samples from 137 patients with cerebral gliomas, 61 WHO grade II and 76 WHO grade III tumors.

Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed microarray-based genome- and transcriptome-wide molecular profiling of primary tumor samples from 137 patients with cerebral gliomas, 61 WHO grade II and 76 WHO grade III tumors.

The PanCancer Browser is a web application for the interactive comparison of molecular landscapes of different cancers provided by the oposSOM analysis pipeline. It complements the single data set-centered browsing tool oposSOM-Browser.

oposSOM is a comprehensive, machine learning based open-source data analysis software combining functionalities such as diversity analyses, biomarker selection, function mining, and visualization. These functionalities are now available as interactive web-browser application for a broader user audience interested in extracting detailed information from high-throughput omics data sets pre-processed by oposSOM. It enables interactive browsing of single-gene and gene set profiles, of molecular
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The Covid‐19 viewer provides an intuitive tool to monitor the development of the pandemic in 188 countries using simple plots. The tool is interactive and enables the user to select different plots for single countries, groups or all of them. It visualizes descriptive features such as slopes or flattening behaviour of epidemic numbers and of their increments to allow a qualitative justification of the current state of the pandemic, e.g. whether it is growing exponentially, stopped due to counter
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Analysis of large-scale molecular biological data using self-organizing maps

Comprehensive analysis of genome-wide molecular data challenges bioinformatics methodology in terms of intuitive visualization with single-sample resolution, biomarker selection, functional information mining and highly granular stratification of sample classes. oposSOM combines those functionalities making use of a comprehensive analysis and visualization strategy based on self-organizing maps (SOM) machine learning
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Contribute to hloefflerwirth/scrat development by creating an account on GitHub.

Background: Covid-19 pandemic is developing worldwide with common dynamics but also with partly marked differences between regions and countries. They are not completely understood, but presumably, provide one clue to find ways to mitigate epidemics until exit strategies to its eradication become available. Method: We provide a monitoring tool available at www.izbi.de. It enables inspection of the dynamic state of the epidemic in 187 countries using trajectories. They visualize transmission and
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