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Health Atlas ID: 7WATJM05G3-0
Location:
Germany
Expertise: Not specified
Tools: Not specified
ORCID: Not specified
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- Projects (2)
- Institutions (1)
- Investigations (1)
- Studies (1)
- Resources (2)
- Publications (10)
- Data files (7+1)
- Models (1+1)
- Documents (1)
The aim of the Head and Neck Group within the Leipzig Research Center for Civilization Diseases (LIFE) is to facilitate improvements in the treatment and care of head and neck cancer patients through insights from molecular studies.
The Head and Neck Group within the Leipzig Research Center for Civilization Diseases (LIFE) investigates the molecular mechanisms and the diagnostic and prognostic factors of head and neck cancer. For this purpose, we collected phenotypic information from about 300
...
Programme: This Project is not associated with a Programme
Public web page: http://life.uni-leipzig.de/
Start date: 1st Jan 2012
End date: 31st Dec 2012
Organisms: Homo sapiens
Human Diseases: head and neck cancer
Goal of the Leipzig Research Center for Civilization Diseases (LIFE) is the investigation of civilization diseases like depression, diabetes, allergies or cardiovascular diseases. For this purpose we collect as much data as possible regarding health and living conditions of the population in Leipzig and provide these data for scientists of the University of Leipzig and other research institutions.
Stratification of head and neck squamous cell carcinomas (HNSCC) based on HPV16 DNA and RNA status
Snapshots: No snapshots
Studies: HNSCC
Resources: HNSCC Clinical Dataset, HNSCC OMICS Data
Stratification of head and neck squamous cell carcinomas (HNSCC) based on HPV16 DNA and RNA status
Investigation: head and neck squamous cell carcinomas
Resources: HNSCC Clinical Dataset, HNSCC OMICS Data
Submitter: René Hänsel
Resource type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
Investigation: head and neck squamous cell carcinomas
Study: HNSCC
Organisms: No organisms
Human Diseases: head and neck squamous cell carcinoma
SOPs: No SOPs
Data files: GSE 65858 CSV, GSE 65858 ODM, GSE 65858 XLS, Gene expression patterns and TP53 mutations are...
Submitter: René Hänsel
Resource type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
Investigation: head and neck squamous cell carcinomas
Study: HNSCC
Organisms: No organisms
Human Diseases: head and neck squamous cell carcinoma
SOPs: No SOPs
Data files: Gene expression patterns and TP53 mutations are...
Abstract (Expand)
Authors: Maciej Rosolowski, Volker Oberle, Peter Ahnert, Petra Creutz, Martin Witzenrath, Michael Kiehntopf, Markus Loeffler, Norbert Suttorp, Markus Scholz
Date Published: 1st Dec 2020
Publication Type: Journal article
Abstract (Expand)
Authors: Manuela Gesell Salazar, Sophie Neugebauer, Tim Kacprowski, Stephan Michalik, Peter Ahnert, Petra Creutz, Maciej Rosolowski, Markus Löffler, Michael Bauer, Norbert Suttorp, Michael Kiehntopf, Uwe Völker
Date Published: 1st Mar 2020
Publication Type: Journal article
DOI: 10.1016/j.jprot.2019.103627
Citation: Journal of Proteomics 214:103627
Abstract (Expand)
Authors: H. Binder, L. Hopp, M. R. Schweiger, S. Hoffmann, F. Juhling, M. Kerick, B. Timmermann, S. Siebert, C. Grimm, L. Nersisyan, A. Arakelyan, M. Herberg, P. Buske, H. Loeffler-Wirth, M. Rosolowski, C. Engel, J. Przybilla, M. Peifer, N. Friedrichs, G. Moeslein, M. Odenthal, M. Hussong, S. Peters, S. Holzapfel, J. Nattermann, R. Hueneburg, W. Schmiegel, B. Royer-Pokora, S. Aretz, M. Kloth, M. Kloor, R. Buettner, J. Galle, M. Loeffler
Date Published: 21st Jul 2017
Publication Type: Not specified
Human Diseases: Lynch syndrome, colorectal cancer
PubMed ID: 28727142
Citation: J Pathol. 2017 Oct;243(2):242-254. doi: 10.1002/path.4948. Epub 2017 Sep 5.
Abstract (Expand)
Authors: G. Wichmann, M. Rosolowski, K. Krohn, M. Kreuz, A. Boehm, A. Reiche, U. Scharrer, D. Halama, J. Bertolini, U. Bauer, D. Holzinger, M. Pawlita, J. Hess, C. Engel, D. Hasenclever, M. Scholz, P. Ahnert, H. Kirsten, A. Hemprich, C. Wittekind, O. Herbarth, F. Horn, A. Dietz, M. Loeffler
PubMed ID: 26095926
Citation: Int J Cancer. 2015 Dec 15;137(12):2846-57. doi: 10.1002/ijc.29649. Epub 2015 Jul 6.
Abstract (Expand)
Authors: R. Wagener, S. M. Aukema, M. Schlesner, A. Haake, B. Burkhardt, A. Claviez, H. G. Drexler, M. Hummel, M. Kreuz, M. Loeffler, M. Rosolowski, C. Lopez, P. Moller, J. Richter, M. Rohde, M. J. Betts, R. B. Russell, S. H. Bernhart, S. Hoffmann, P. Rosenstiel, M. Schilhabel, M. Szczepanowski, L. Trumper, W. Klapper, R. Siebert
PubMed ID: 26173642
Citation: Genes Chromosomes Cancer. 2015 Sep;54(9):555-64. doi: 10.1002/gcc.22268. Epub 2015 Jul 14.
Based on the assumption that molecular mechanisms involved in cancerogenesis are characterized by groups of coordinately expressed genes, we developed and validated a novel method for analyzing transcriptional data called Correlated Gene Set Analysis (CGSA). Using 50 extracted gene sets we identified three different profiles of tumors in a cohort of 364 Diffuse large B-cell (DLBCL) and related mature aggressive B-cell lymphomas other than Burkitt lymphoma. The first profile had high level of
...
Creator: Maciej Rosolowski
Submitter: Christoph Beger
Data file type: Transcriptomic Data
Human Diseases: diffuse large B-cell lymphoma
Investigations: No Investigations
Studies: No Studies
Resources: No Resources
Our first objective was to compare the molecular features of subgroups of HNSCC defined by their HPV16 DNA and RNA status. The second objective was to identify gene expression subtypes in HNSCC and to correlate them with other characteristics of the patients.
HPV DNA and RNA status, mutations of 50 genes, survival and other clinical characteristics of 270 patients with head and neck cancer.
Investigations: head and neck squamous cell carcinomas
Studies: HNSCC
Resources: HNSCC Clinical Dataset
Our first objective was to compare the molecular features of subgroups of HNSCC defined by their HPV16 DNA and RNA status. The second objective was to identify gene expression subtypes in HNSCC and to correlate them with other characteristics of the patients.
HPV DNA and RNA status, mutations of 50 genes, survival and other clinical characteristics of 270 patients with head and neck cancer.
Investigations: head and neck squamous cell carcinomas
Studies: HNSCC
Resources: HNSCC Clinical Dataset
Our first objective was to compare the molecular features of subgroups of HNSCC defined by their HPV16 DNA and RNA status. The second objective was to identify gene expression subtypes in HNSCC and to correlate them with other characteristics of the patients.
HPV DNA and RNA status, mutations of 50 genes, survival and other clinical characteristics of 270 patients with head and neck cancer.
Investigations: head and neck squamous cell carcinomas
Studies: HNSCC
Resources: HNSCC Clinical Dataset
Our first objective was to compare the molecular features of subgroups of HNSCC defined by their HPV16 DNA and RNA status. The second objective was to identify gene expression subtypes in HNSCC and to correlate them with other characteristics of the patients.
HPV DNA and RNA status, mutations of 50 genes, survival and other clinical characteristics of 270 patients with head and neck cancer.
Creator: Maciej Rosolowski
Submitter: Christoph Beger
Data file type: Clinical Data
Human Diseases: head and neck squamous cell carcinoma
Investigations: head and neck squamous cell carcinomas
Studies: HNSCC
Resources: HNSCC Clinical Dataset
This Shiny-App implements the calculation of several CAP (Community-Aquired-Pneumonia) severity scores for one or multiple patients based on user-updated data.
Creators: Markus Scholz, Maciej Rosolowski, Carl Beuchel
Submitter: Carl Beuchel
Model type: Algebraic equations
Model format: R package
Environment: Shiny
Organism: Homo sapiens
Human Disease: pneumonia
Investigations: No Investigations
Studies: No Studies
Resources: No Resources
Creator: Maciej Rosolowski
Submitter: René Hänsel
Investigations: No Investigations
Studies: No Studies
Resources: No Resources