External ventricular drain infections: risk factors and outcome

Abstract:

External ventricular drainage (EVD) is frequently used in neurosurgery to drain cerebrospinal fluid in patients with raised intracranial pressure. We performed a retrospective single center study in order to evaluate the incidence of EVD-related infections and to identify underlying risk factors. 246 EVDs were placed in 218 patients over a 30-month period. EVD was continued in median for 7 days (range 1-44). The cumulative incidence of EVD-related infections was 8.3% (95% CI, 5.3-12.7) with a device-associated infection rate of 10.4 per 1000 drainage days (95% CI, 6.2-16.5). The pathogens most commonly identified were coagulase-negative Staphylococcus (62%) followed by Enterococcus spp. (19%). Patients with an EVD-related infection had a significantly longer ICU (11 versus 21 days, P \textless 0.01) and hospital stay (20 versus 28.5 days, P \textless 0.01) than patients without. Median total duration of external drainage was twice as long in patients with EVD-related infection (6 versus 12 days, P \textless 0.01). However, there was no significant difference in the duration between first EVD placement and the occurrence of EVD-related infection and EVD removal in patients without EVD-related infection (6 versus 7 days, P = 0.87), respectively. Interestingly no risk factor for EVD-related infection could be identified in our cohort of patients.

DOI: 10.1155/2014/708531

Projects: SepNet - German Competence Network Sepsis

Publication type: Journal article

Journal: Interdisciplinary perspectives on infectious diseases

Human Diseases: Disease by infectious agent

Citation: Interdisciplinary Perspectives on Infectious Diseases 2014:1-6

Date Published: 2014

Registered Mode: imported from a bibtex file

Authors: S. Hagel, T. Bruns, M. W. Pletz, C. Engel, R. Kalff, C. Ewald

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Hagel, S., Bruns, T., Pletz, M. W., Engel, C., Kalff, R., & Ewald, C. (2014). External Ventricular Drain Infections: Risk Factors and Outcome. In Interdisciplinary Perspectives on Infectious Diseases (Vol. 2014, pp. 1–6). Hindawi Limited. https://doi.org/10.1155/2014/708531
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Created: 15th Jul 2020 at 14:33

Last updated: 7th Dec 2021 at 17:58

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