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Goal of the Leipzig Research Center for Civilization Diseases (LIFE) is the investigation of civilization diseases like depression, diabetes, allergies or cardiovascular diseases. For this purpose we collect as much data as possible regarding health and living conditions of the population in Leipzig and provide these data for scientists of the University of Leipzig and other research institutions.
This population-based study examined 10,000 participants randomly selected from the Leipzig population (2011 to 2014). A follow-up is to be carried out from 2017 - 2020. The study mainly included people aged between 40 and 79. All participants underwent a 6-hour study program and people over 60 years of age were invited two more times to in-depth study of cognition and depression and the brain (MRI, EEG). Extensive measurements of genome, metabolome and transcriptome are available. The LIFE-ADULT
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Programme: Epidemiology
Public web page: http://life.uni-leipzig.de/en/adults/life_adult.html
Start date: 1st Jan 2009
Organisms: Homo sapiens
Human Diseases: mood disorder, dementia, coronary artery disease, obesity
Abstract (Expand)
Authors: Felix S Hussenoeder, Ines Conrad, Susanne Roehr, Heide Glaesmer, Andreas Hinz, Cornelia Enzenbach, Christoph Engel, Veronika Witte, Matthias L Schroeter, Markus Loeffler, Joachim Thiery, Arno Villringer, Steffi G Riedel-Heller, Francisca S Rodriguez
PubMed ID: 31129995
Citation: Aging & Mental Health. 2019 May 25:1-7. doi: 10.1080/13607863.2019.1617244.
Abstract (Expand)
Authors: M. Yahiaoui-Doktor, T. Luck, S. G. Riedel-Heller, M. Loeffler, K. Wirkner, C. Engel
PubMed ID: 31077241
Citation: Alzheimers Res Ther. 2019 May 10;11(1):43. doi: 10.1186/s13195-019-0494-z.
Abstract (Expand)
Authors: A. Hinz, T. Luck, S. G. Riedel-Heller, P. Y. Herzberg, C. Rolffs, K. Wirkner, C. Engel
Date Published: 21st Nov 2018
Publication Type: Not specified
PubMed ID: 30456541
Citation: Eur Arch Otorhinolaryngol. 2019 Feb;276(2):389-395. doi: 10.1007/s00405-018-5210-2. Epub 2018 Nov 20.
Abstract (Expand)
Authors: J. Stein, S. Rohr, T. Luck, M. Lobner, S. G. Riedel-Heller
Date Published: 30th Aug 2017
Publication Type: Journal article
Human Diseases: disease of mental health
PubMed ID: 28851002
Citation: Psychiatr Prax. 2018 Jan;45(1):7-15. doi: 10.1055/s-0043-117050. Epub 2017 Aug 29.
Abstract (Expand)
Authors: A. Loffler, T. Luck, F. S. Then, C. Luck-Sikorski, A. Pabst, P. Kovacs, Y. Bottcher, J. Breitfeld, A. Tonjes, A. Horstmann, M. Loffler, C. Engel, J. Thiery, A. Villringer, M. Stumvoll, S. G. Riedel-Heller
Date Published: 25th Jul 2017
Publication Type: Journal article
PubMed ID: 28735590
Citation: Public Health Nutr. 2017 Oct;20(15):2706-2712. doi: 10.1017/S1368980017001653. Epub 2017 Jul 24.