Goal of the Leipzig Research Center for Civilization Diseases (LIFE) is the investigation of civilization diseases like depression, diabetes, allergies or cardiovascular diseases. For this purpose we collect as much data as possible regarding health and living conditions of the population in Leipzig and provide these data for scientists of the University of Leipzig and other research institutions.
This population-based study examined 10,000 participants randomly selected from the Leipzig population (2011 to 2014). A follow-up is to be carried out from 2017 - 2020. The study mainly included people aged between 40 and 79. All participants underwent a 6-hour study program and people over 60 years of age were invited two more times to in-depth study of cognition and depression and the brain (MRI, EEG). Extensive measurements of genome, metabolome and transcriptome are available. The LIFE-ADULT
Authors: Felix S Hussenoeder, Ines Conrad, Susanne Roehr, Heide Glaesmer, Andreas Hinz, Cornelia Enzenbach, Christoph Engel, Veronika Witte, Matthias L Schroeter, Markus Löffler, Joachim Thiery, Arno Villringer, Steffi Gerlinde Riedel-Heller, Francisca S Rodriguez
Date Published: 25th May 2019
Journal: Aging & mental health
Human Diseases: mental depression
PubMed ID: 31129995
Citation: Aging & Mental Health. 2019 May 25:1-7. doi: 10.1080/13607863.2019.1617244.
Date Published: 30th Aug 2017
Journal: Psychiatr Prax
Human Diseases: disease of mental health
PubMed ID: 28851002
Citation: Psychiatr Prax. 2018 Jan;45(1):7-15. doi: 10.1055/s-0043-117050. Epub 2017 Aug 29.
PubMed ID: 28389488
Citation: BMJ Open. 2017 Apr 7;7(4):e013630. doi: 10.1136/bmjopen-2016-013630.
PubMed ID: 27814674
Citation: BMC Geriatr. 2016 Nov 4;16(1):180. doi: 10.1186/s12877-016-0353-8.
Authors: Susanne Roehr, Tobias Luck, K. Heser, A. Fuchs, A. Ernst, B. Wiese, J. Werle, H. Bickel, C. Brettschneider, A. Koppara, M. Pentzek, C. Lange, J. Prokein, S. Weyerer, E. Mosch, H. H. Konig, W. Maier, M. Scherer, F. Jessen, Steffi Gerlinde Riedel-Heller
Date Published: 15th Jan 2016
Journal: PLoS One
Human Diseases: dementia
PubMed ID: 26766555
Citation: PLoS One. 2016 Jan 14;11(1):e0147050. doi: 10.1371/journal.pone.0147050. eCollection 2016.