Goal of the Leipzig Research Center for Civilization Diseases (LIFE) is the investigation of civilization diseases like depression, diabetes, allergies or cardiovascular diseases. For this purpose we collect as much data as possible regarding health and living conditions of the population in Leipzig and provide these data for scientists of the University of Leipzig and other research institutions.
This population-based study examined 10,000 participants randomly selected from the Leipzig population (2011 to 2014). A follow-up is to be carried out from 2017 - 2020. The study mainly included people aged between 40 and 79. All participants underwent a 6-hour study program and people over 60 years of age were invited two more times to in-depth study of cognition and depression and the brain (MRI, EEG). Extensive measurements of genome, metabolome and transcriptome are available. The LIFE-ADULT
Authors: S. Meyer, Karsten Müller, K. Stuke, S. Bisenius, J. Diehl-Schmid, F. Jessen, J. Kassubek, J. Kornhuber, A. C. Ludolph, J. Prudlo, A. Schneider, K. Schuemberg, I. Yakushev, M. Otto, M. L. Schroeter
Date Published: 29th Mar 2017
Journal: Neuroimage Clin
Human Diseases: frontotemporal dementia
PubMed ID: 28348957
Citation: Neuroimage Clin. 2017 Feb 6;14:656-662. doi: 10.1016/j.nicl.2017.02.001. eCollection 2017.
Date Published: 2nd Feb 2016
Journal: Neurobiol Aging
Human Diseases: Not specified
PubMed ID: 26827656
Citation: Neurobiol Aging. 2016 Feb;38:181-187. doi: 10.1016/j.neurobiolaging.2015.11.003. Epub 2015 Nov 11.