Models
The PanCancer Browser is a web application for the interactive comparison of molecular landscapes of different cancers provided by the oposSOM analysis pipeline. It complements the single data set-centered browsing tool oposSOM-Browser.
Creator: Henry Löffler-Wirth
Submitter: Henry Löffler-Wirth
Model type: Self-Organizing Map
Model format: R package
Environment: Shiny
The PREMM1,2,6 has been developed as a pretest to decide whether patients suspected of having Lynch syndrome should be tested for germline mismatch repair gene mutations. "PREMM1,2,6" is a logistic regression model. It calculates the risk of having a mutation in the mismatch repair genes MLH1, MSH2 and MSH6 (for single genes and overall) based on the personal and familial cancer history of the proband (colorectal, endometrial, and other Lynch syndrome related cancers).
Creators: Silke Zachariae, Christoph Engel, Kastrinos et al.
Submitter: Silke Zachariae
Model type: Not specified
Model format: R package
Environment: Shiny
The PREMM5 has been developed as a pretest to decide whether patients suspected of having Lynch syndrome should be tested for germline mismatch repair gene mutations. In contrast to "PREMM1,2,6" it can be used to predict mutation probabilities in unaffected index patients. "PREMM5" is a logistic regression model. It calculates the risk of having a mutation in the mismatch repair genes MLH1, MSH2/EPCAM, MSH6 and PMS2 (for single genes and overall) based on the personal and familial cancer history ...
Creators: Silke Zachariae, Christoph Engel, Kastrinos et al.
Submitter: Silke Zachariae
Model type: Not specified
Model format: R package
Environment: Shiny