Interactive Pathway Activity Analysis Platform
Version 1

The platform is intended for visualization of expression- and mutation-driven changes in biological pathway activities in cancer datasets available in ICGC. The impact of somatic mutations on protein-protein interactions were calculated using Mechismo. Overall activity of biological pathway was evaluated using Pathway Signal Flow algorithm. The application provides interactive heatmaps for pathway output sink node activities and pathway images with mapped affected interactions and output node activities.

LHA-ID: 7QWM5X316P-7

1 item is associated with this Model:

Human Disease: Not specified

Model type: Not specified

Model format: R package

Execution or visualisation environment: RStudio

Model image: No image specified

Help
help Contributor and Creators

help Other creators

Siras Hakobyan
Activity

Views: 120

Created: 20th May 2019 at 11:24

Last updated: 23rd Aug 2019 at 06:21

Last used: 24th Aug 2019 at 05:55

help Attributions

None

Related items

Powered by
(v.1.9.0)
Copyright © 2008 - 2019 The University of Manchester and HITS gGmbH
Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig