Interactive Pathway Activity Analysis Platform
Version 1

The platform is intended for visualization of expression- and mutation-driven changes in biological pathway activities in cancer datasets available in ICGC. The impact of somatic mutations on protein-protein interactions were calculated using Mechismo. Overall activity of biological pathway was evaluated using Pathway Signal Flow algorithm. The application provides interactive heatmaps for pathway output sink node activities and pathway images with mapped affected interactions and output node activities.

Health Atlas ID: 7QWM5X316P-7

1 item is associated with this Model:

Organism: Homo sapiens

Human Disease: Cancer

Model type: Self-Organizing Map

Model format: R package

Execution or visualisation environment: Shiny

Model image: No image specified

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Views: 1009

Created: 20th May 2019 at 11:24

Last updated: 17th Jun 2020 at 14:01

Last used: 28th Feb 2021 at 02:02

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