Interactive Pathway Activity Analysis Platform Version 1
External LinkThe platform is intended for visualization of expression- and mutation-driven changes in biological pathway activities in cancer datasets available in ICGC. The impact of somatic mutations on protein-protein interactions were calculated using Mechismo. Overall activity of biological pathway was evaluated using Pathway Signal Flow algorithm. The application provides interactive heatmaps for pathway output sink node activities and pathway images with mapped affected interactions and output node activities.
LHA-ID: 7QWM5X316P-7
1 item is associated with this Model:
Human Disease: Not specified
Model type: Not specified
Model format: R package
Execution or visualisation environment: RStudio
Model image: No image specified
Export PNG
Download
Contributor and Creators
Other creators
Views: 120
Created: 20th May 2019 at 11:24
Last updated: 23rd Aug 2019 at 06:21
Last used: 24th Aug 2019 at 05:55
AttributionsNone
Related items
https://orcid.org/0000-0002-1166-0368
During 2004 and 2012 the german cancer aid supported the german glioma network (GGN). The GGN is a consortium where university hospitals with clinical focus in neuro-oncology, reference centers for neuroradiology, neuropathology, molecular diagnostics and biometry cooperate. Thanks to the long-term support it was possible to build a network of competence centers for the treatment of brain tumors in Germany wich is characterized by a interdisciplinary collaboration of all specialist disciplines
...
