Interactive Pathway Activity Analysis Platform
Version 1

The platform is intended for visualization of expression- and mutation-driven changes in biological pathway activities in cancer datasets available in ICGC. The impact of somatic mutations on protein-protein interactions were calculated using Mechismo. Overall activity of biological pathway was evaluated using Pathway Signal Flow algorithm. The application provides interactive heatmaps for pathway output sink node activities and pathway images with mapped affected interactions and output node activities.

LHA-ID: 7QWM5X316P-7

1 item is associated with this Model:

Human Disease: Not specified

Model type: Not specified

Model format: R package

Execution or visualisation environment: RStudio

Model image: No image specified

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Siras Hakobyan

Views: 37

Created: 20th May 2019 at 11:24

Last updated: 20th May 2019 at 11:24

Last used: 25th Jun 2019 at 11:05

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Leipzig Health Atlas

The Leipzig Health Atlas is an alliance of medical ontologists, medical systems biologists and clinical trials groups to design and implement a multi-functional and quality-assured atlas. It provides models, data and metadata on specific use cases from medical research fields.

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