Zur Bedeutung der Genvariante PTPN22 620W für die Rheumatologie
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BiBTeXPTPN22 620W is regarded as the second most important risk factor for type 1 diabetes and rheumatoid arthritis. Here we describe aspects of the molecular biology of the enzyme and its function, the geographical distribution of the 620W variant, as well as its importance in less frequent rheumatic diseases.
DOI: 10.1007/s00393-008-0381-7
Projects: Genetical Statistics and Systems Biology
Publication type: Journal article
Journal: Zeitschrift für Rheumatologie
Human Diseases: No Human Disease specified
Citation: Z. Rheumatol. 67(7):593-595
Date Published: 1st Nov 2008
Registered Mode: imported from a bibtex file
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Created: 14th Sep 2020 at 13:07
Last updated: 7th Dec 2021 at 17:58
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The group is interested in omic-level studies including the genome, methylome, transcriptome, and metabolome of the general population as well as of various diseases including cardiovascular diseases, pneumonia, sepsis, obesity, and brain cancers. Additionally, we aim at transfering results of biomathematical model simulations into clinical practice e.g. by haematopoietic growth-factor opimization during cytotoxic chemotherapy and optimization of EPO applications in chronic kidney disease.
The ...
Programme: This Project is not associated with a Programme
Public web page: http://www.imise.uni-leipzig.de/en/Groups/GenStat/
Start date: 1st Jan 2013
https://orcid.org/0000-0002-5307-6936
