Ulrike Holdgrün
LHA ID: 91TY81P2XK-0
Location:
Germany
ORCID:
https://orcid.org/0009-0007-0838-6277
Joined: 8th Jul 2026
Expertise: Not specified
Tools: Not specified
Project roles
Project administrator
Their tagsRelated items
Diabetes mellitus (DM) is a metabolic disease based on insulin resistance or deficiency, characterized by chronically elevated blood glucose levels and associated with an increased risk of severe concomitant and secondary diseases. There are two main forms, DM type 1 and type 2, the latter of which can have highly heterogeneous manifestations, so that a more refined classification can contribute to more individualized treatment of high-risk patients with a potentially worse inpatient outcome.This ...
Programme: Medical Data Science
Public web page: Not specified
As part of the DiaClusT project, we developed a multinomial logistic regression classifier to assign patients to distinct type 2 diabetes clusters based on their clinical characteristics. The current approach, including age, sex, BMI, HbA1c, and triglyceride levels, achieved an overall accuracy of 92%, with sensitivity, specificity, and F1-score all exceeding 0.87. The model’s robust performance highlights the potential of incorporating cluster assignment into routine admission workflows, ...
Creator: Ulrike Holdgrün
Submitter: Ulrike Holdgrün
Model type: Linear equations
Model format: R package
Environment: Shiny
Welcome to the Department for Medical Data Sciences at the University Medical Center in Leipzig. We are an interdisciplinary team focusing on medical data sciences in order to increase the value for the patients. In this way, we are mainly working with medical data. Our focus is twofold. On the one hand, we are working on different facets of computing infrastructures allowing us to prepare and analyze medical data, such as for distributed computing. Secondly, we focus on the analysis of medical ...
Projects: DiaClusT, Synthetica: generation and evaluation of synthetic data, Prediction model of Length of Stay and probability of rehospitalization, LEUKO-EXPERT
Web page: https://www.uniklinikum-leipzig.de/einrichtungen/medical-data-science/en/team
