Phenotype Algorithms

LIFE-LHNG 803RVNUTA1-1

Description:

HPV DNA and RNA status, mutations of 50 genes, survival and other clinical characteristics of 270 patients with head and neck cancer described in Wichmann et al. Int. J. Canc. 2015

Description:
No description specified
ID Title Unit Formula Range Score
AKT1_MUTATION AKT1 mutation
AKT1_MUTATION_1 Mutant = 1
AKT1_MUTATION_0 Wild type = 0
APC_MUTATION APC mutation
APC_MUTATION_1 Mutant = 1
APC_MUTATION_0 Wild type = 0
ATM_MUTATION ATM mutation
ATM_MUTATION_1 Mutant = 1
ATM_MUTATION_0 Wild type = 0
CDH1_MUTATION CDH1 mutation
CDH1_MUTATION_1 Mutant = 1
CDH1_MUTATION_0 Wild type = 0
CDKN2A_MUTATION CDKN2A mutation
CDKN2A_MUTATION_0 Wild type = 0
CDKN2A_MUTATION_1 Mutant = 1
CSF1R_MUTATION CSF1R mutation
CSF1R_MUTATION_1 Mutant = 1
CSF1R_MUTATION_0 Wild type = 0
EGFR_MUTATION EGFR mutation
EGFR_MUTATION_0 Wild type = 0
EGFR_MUTATION_1 Mutant = 1
ERBB2_MUTATION ERBB2 mutation
ERBB2_MUTATION_1 Mutant = 1
ERBB2_MUTATION_0 Wild type = 0
ERBB4_MUTATION ERBB4 mutation
ERBB4_MUTATION_0 Wild type = 0
ERBB4_MUTATION_1 Mutant = 1
FBXW7_MUTATION FBXW7 mutation
FBXW7_MUTATION_0 Wild type = 0
FBXW7_MUTATION_1 Mutant = 1
FGFR2_MUTATION FGFR2 mutation
FGFR2_MUTATION_1 Mutant = 1
FGFR2_MUTATION_0 Wild type = 0
FGFR3_MUTATION FGFR3 mutation
FGFR3_MUTATION_1 Mutant = 1
FGFR3_MUTATION_0 Wild type = 0
FLT3_MUTATION FLT3 mutation
FLT3_MUTATION_1 Mutant = 1
FLT3_MUTATION_0 Wild type = 0
GNA11_MUTATION GNA11 mutation
GNA11_MUTATION_0 Wild type = 0
GNA11_MUTATION_1 Mutant = 1
HRAS_MUTATION HRAS mutation
HRAS_MUTATION_0 Wild type = 0
HRAS_MUTATION_1 Mutant = 1
IDH1_MUTATION IDH1 mutation
IDH1_MUTATION_0 Wild type = 0
IDH1_MUTATION_1 Mutant = 1
JAK3_MUTATION JAK3 mutation
JAK3_MUTATION_0 Wild type = 0
JAK3_MUTATION_1 Mutant = 1
KIT_MUTATION KIT mutation
KIT_MUTATION_0 Wild type = 0
KIT_MUTATION_1 Mutant = 1
NOTCH1_MUTATION NOTCH1 mutation
NOTCH1_MUTATION_1 Mutant = 1
NOTCH1_MUTATION_0 Wild type = 0
NRAS_MUTATION NRAS mutation
NRAS_MUTATION_0 Wild type = 0
NRAS_MUTATION_1 Mutant = 1
PIK3CA_MUTATION PIK3CA mutation
PIK3CA_MUTATION_1 Mutant = 1
PIK3CA_MUTATION_0 Wild type = 0
PTEN_MUTATION PTEN mutation
PTEN_MUTATION_1 Mutant = 1
PTEN_MUTATION_0 Wild type = 0
RB1_MUTATION RB1 mutation
RB1_MUTATION_1 Mutant = 1
RB1_MUTATION_0 Wild type = 0
RET_MUTATION RET mutation
RET_MUTATION_0 Wild type = 0
RET_MUTATION_1 Mutant = 1
SMAD4_MUTATION SMAD4 mutation
SMAD4_MUTATION_0 Wild type = 0
SMAD4_MUTATION_1 Mutant = 1
SMO_MUTATION SMO mutation
SMO_MUTATION_0 Wild type = 0
SMO_MUTATION_1 Mutant = 1
SRC_MUTATION SRC mutation
SRC_MUTATION_0 Wild type = 0
SRC_MUTATION_1 Mutant = 1
STK11_MUTATION STK11 mutation
STK11_MUTATION_0 Wild type = 0
STK11_MUTATION_1 Mutant = 1
TP53_MUTATION TP53 mutation
TP53_MUTATION_Non-disruptive Non-disruptive = Non-disruptive
TP53_MUTATION_Disruptive Disruptive = Disruptive
TP53_MUTATION_WT Wild type = WT
VHL_MUTATION VHL mutation
VHL_MUTATION_0 Wild type = 0
VHL_MUTATION_1 Mutant = 1
Description:
No description specified
ID Title Unit Formula Range Score
DISTANT_METASTASIS Distant metastasis
DISTANT_METASTASIS_0 No = 0
DISTANT_METASTASIS_1 Yes = 1
N_CATEGORY N (nodal) category
N_CATEGORY_0 0 = 0
N_CATEGORY_1 1 = 1
N_CATEGORY_3 3 = 3
N_CATEGORY_2c 2c = 2c
N_CATEGORY_2b 2b = 2b
N_CATEGORY_2a 2a = 2a
TREATMENT Treatment
TREATMENT_mono Unimodal = mono
TREATMENT_multi Multimodal = multi
TREATMENT_palliative Palliative = palliative
TUMOR_SITE Tumor site
TUMOR_SITE_Cavum_Oris Oral cavity = Cavum Oris
TUMOR_SITE_Larynx Larynx = Larynx
TUMOR_SITE_Oropharynx Oropharynx = Oropharynx
TUMOR_SITE_Hypopharynx Hypopharynx = Hypopharynx
TUMOR_TYPE Tumor type
TUMOR_TYPE_Primary Primary = Primary
TUMOR_TYPE_Relapse Locoregional relapse = Relapse
TUMOR_TYPE_Secondary Secondary primary = Secondary
T_CATEGORY T (tumor) category
T_CATEGORY_1 1 = 1
T_CATEGORY_4b 4b = 4b
T_CATEGORY_4a 4a = 4a
T_CATEGORY_2 2 = 2
T_CATEGORY_3 3 = 3
UICC_STAGE UICC stage
UICC_STAGE_I I = I
UICC_STAGE_IVC IVC = IVC
UICC_STAGE_IVB IVB = IVB
UICC_STAGE_IVA IVA = IVA
UICC_STAGE_III III = III
UICC_STAGE_II II = II
Description:
No description specified
ID Title Unit Formula Range Score
ALCOHOL Alcohol
ALCOHOL_>60 >60 g/day = >60
ALCOHOL_no No = no
ALCOHOL_1_to_30 1 to 30 g/day = 1 to 30
ALCOHOL_31_to_60 31 to 60 g/day = 31 to 60
PACKYEARS Packyears packyears
SMOKING Smoking
SMOKING_No No = No
SMOKING_Yes Yes = Yes
Description:
No description specified
ID Title Unit Formula Range Score
HPV16_DNA_RNA HPV16 DNA RNA status
HPV16_DNA_RNA_DNA+RNA+ DNA+RNA+ = DNA+RNA+
HPV16_DNA_RNA_DNA+RNA- DNA+RNA- = DNA+RNA-
HPV16_DNA_RNA_DNA- DNA- = DNA-
HPV_DNA HPV DNA status
HPV_DNA_HPV16 HPV16 DNA+ = HPV16
HPV_DNA_Other_HPV Other HPV = Other HPV
HPV_DNA_Negative HPV DNA- = Negative
Description:
No description specified
ID Title Unit Formula Range Score
AGE Age years
GENDER Gender
GENDER_F Female = F
GENDER_M Male = M
ID ID
Description:
No description specified
ID Title Unit Formula Range Score
OS Overall survival day
OS_EVENT Overall survival event
OS_EVENT_TRUE TRUE = TRUE
OS_EVENT_FALSE FALSE = FALSE
PFS Progression-free survival day
PFS_EVENT Progression-free survival event
PFS_EVENT_FALSE FALSE = FALSE
PFS_EVENT_TRUE TRUE = TRUE
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