Toolbox for Genetic Risk Prediction
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Figure 1: Pedigree with multiple and early onset cases of breast cancer (BC) and ovarian cancer (OC)
In a first step, the genetic counselor has to decide whether genetic testing should be offered to this family or not. This decision depends on the expected probability to find a disease-causing mutation. Genetic risk models can be used to predict this risk for individual families and thus to assist the counselor in clinical decision making.
Pathological information is entered as follows. After completion of data entry, the result can be calculated.