Pathway signal flow

Pathway signal flow (PSF) algorithm calculates activity of cellular signalling cascades for selected pathways (KEGG database). Reports show an overview about the pathways along with genes contained in data (p.1 in PDF) and sink nodes (p.2). Additionally, the signal strength is visualized for each histological subtype (p.3 ff).

Selected pathway: Apoptosis B cell receptor signaling pathway Cell cycle Citrate cycle (TCA cycle) Glycolysis / Gluconeogenesis Hedgehog signaling pathway Insulin signaling pathway Jak-STAT signaling pathway MAPK signaling pathway mTOR signaling pathway Natural killer cell mediated cytotoxicity NF-kappa B signaling pathway Notch signaling pathway p53 signaling pathway PI3K-Akt signaling pathway Ras signaling pathway T cell receptor signaling pathway Toll-like receptor signaling pathway Wnt signaling pathway