We present an extensive and detailed study on the gene expression landscape of peripheral blood of healthy individuals based on transcriptome data of 3,388 individuals screened in the population study LIFE between 2011 and 2014. For analysis we applied a neural network technique using self-organizing maps (SOM). Our home-made R-program ‘oposSOM’ enables to reduce the dimension of expression data from tens of thousands of genes to a few thousand ‘meta-genes’ and generates portraits of transcriptional activity that allowed us the sample-to-sample comparison of expression patterns.
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Created: 20th May 2019 at 13:16
Last updated: 20th May 2019 at 13:16
Last used: 31st Oct 2024 at 23:09
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Version 1 Created 20th May 2019 at 13:16 by Christoph Beger
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