Data files
This workspace contains all data generated by the combiSOM analysis of patient-matched gene expression, DNA-methylation and copy number variation (CNV) of 121 lower grade glioma (LGG) specimen.
Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed microarray-based genome- and transcriptome-wide molecular profiling of primary tumor samples from 137 patients with cerebral gliomas, 61 WHO grade II and 76 WHO grade III tumors.
Creators: Henry Löffler-Wirth, Markus Kreuz
Submitter: Christoph Beger
Data file type: Genomic Data
Human Diseases: brain glioma
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Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed Methylation profiling of primary tumor samples from 122 patients with cerebral gliomas with WHO grade II and grade III tumors.
Creators: Hans Binder, Markus Kreuz, Henry Löffler-Wirth
Submitter: Christoph Beger
Data file type: Methylation Data
Human Diseases: brain glioma
Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed Methylation profiling of primary tumor samples from 122 patients with cerebral gliomas with WHO grade II and grade III tumors.
Creators: Hans Binder, Henry Löffler-Wirth, Markus Kreuz
Submitter: Christoph Beger
Data file type: Methylation Data
Human Diseases: brain glioma
Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed microarray-based genome- and transcriptome-wide molecular profiling of primary tumor samples from 137 patients with cerebral gliomas, 61 WHO grade II and 76 WHO grade III tumors.
Creators: Hans Binder, Henry Löffler-Wirth
Submitter: Henry Löffler-Wirth
Data file type: SOM Data
Human Diseases: brain glioma
External LinkProgression free survival and overall survival of patients with brain tumors dependent on IDH1 mutation, methyltransferase (MGMT) methylation, age, WHO diagnosis and combinations of these factors.
Creator: Bettina Hentschel
Submitter: Christoph Beger
Data file type: Clinical Data
Human Diseases: brain glioma, brain glioblastoma multiforme
For this study, we screened prospectively recruited patients with a histopathological reference diagnosis of cerebral tumors of WHO grade II and III, known KPS at diagnosis, information on extent of resection by early postoperative neuroimaging, available frozen tissue specimens from the initial operation, and documented clinical outcome.
Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological ...
