Models
Age-stratified numbers of COVID-19 testpositives and deaths
This work was done as part of the NFDI4Health Task Force COVID-19 (nfdi4health.de). We gratefully acknowledge the financial support of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – Project Number 451265285.
Creators: Holger Kirsten, René Hänsel
Submitter: René Hänsel
Model type: Graphical model
Model format: R package
Environment: Shiny
Introduction On this homepage we provide a web-based tool to calculate prognostic scores on haematopoietic toxicity for 6 cycles CHOP-like regimen in patients with aggressive NHL. As we used for this analysis the data collected within the NHL-B1 and NHL-B2 trials of the DSHNHL as described in detail in Pfreundschuh et al. the predictions are valid for similar patient populations.
Description We offer two types of models. Pre-treatment models include beside the therapy regimen only prognostic ...
Creator: Marita Ziepert
Submitter: René Hänsel
Model type: Not specified
Model format: Not specified
Environment: Not specified
Large scale epidemiological studies, such as LIFE-ADULT, including thousands of participants with a multitude of novel QT assessments allow to define reference values. Reference values are typically used in quality control to find outliers in a specified data volume or to evaluate a given measurement value regarding its pathologic value. Measuring the hand grip strength is a standard assessment in LIFE, for which is no or little prior knowledge regarding reference values available.
Based on the ...
Creator: Toralf Kirsten
Submitter: René Hänsel
Model type: Not specified
Model format: R package
Environment: Not specified
Implementation of recently developed dynamic mathematical models of normal and leukemic hematopoiesis to practically impact clinical decision- making.
Fitting available individual patients information, prediction of next-cycle thrombopenia caused by CHOEP treatment based on the individual fits of the preceeding treatment cycles, changing next-cycle relative dosing, posponement of the next cycle, changing follow-up period, visualization of data and simulation
Creator: Markus Scholz
Submitter: René Hänsel
Model type: Not specified
Model format: R package
Environment: Not specified
This package should simplify the translation of the classifications reported in Wichmann et al. 2015 to other data sets of head and neck cancers.
Classification of head and neck tumor samples into HPV-positive and negative samples based on their gene expression. Classification of the samples into molecular subgroups reported in Wichmann et al. 2015
Creator: Maciej Rosolowski
Submitter: René Hänsel
Model type: Not specified
Model format: R package
Environment: Not specified
oposSOM is a comprehensive, machine learning based open-source data analysis software combining functionalities such as diversity analyses, biomarker selection, function mining, and visualization. These functionalities are now available as interactive web-browser application for a broader user audience interested in extracting detailed information from high-throughput omics data sets pre-processed by oposSOM. It enables interactive browsing of single-gene and gene set profiles, of molecular ...
Creator: Henry Löffler-Wirth
Submitter: René Hänsel
Model type: Self-Organizing Map
Model format: R package
Environment: Shiny
Emerging health geography research analyzes and visualizes health behaviors and outcomes in relation to urban environmental data and related official statistics to produce “health reports” for specific areas. This can be extended to developments in urban planning, e.g., to identify districts or neighborhoods for social investments or restrictions.
We mapped anthropometric data the large LIFE Adult population (10,000 participants) onto the Leipzig map. In particular, we derived the body mass index ...
Creator: Ying-Chi Lin
Submitter: René Hänsel
Model type: Not specified
Model format: Not specified
Environment: Not specified
This is an interactive version of figure 4 of the publication „Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood“.
Creator: Markus Scholz
Submitter: René Hänsel
Model type: Not specified
Model format: R package
Environment: Not specified
All studies and research projects those data are hosted by the Leipzig Health Atlas should follow the FAIR standard. Thus, data are findable, accessible, interoperable, and reusable. To follow the FAIR standard, all data need to be described by rich metadata, on the technical and semantical level. These metadata can then be used to query and search for data elements in a single study or over all studies.
We provide the LHA data portal allowing to searching and accessing data elements in single ...
Creator: Toralf Kirsten
Submitter: René Hänsel
Model type: Not specified
Model format: Not specified
Environment: Not specified
Emerging health geography research analyzes and visualizes health behaviors and outcomes in relation to urban environmental data and related official statistics to produce “health reports” for specific areas.
We mapped measured hand grip data of the large LIFE Adult population (10,000 participants) onto the Leipzig map. In particular, we locate each participant at the time of participation in Leipzig and, thus, can derive hand grip strength averages (incl. mean, median) per specific city districts. ...
Creator: Toralf Kirsten
Submitter: René Hänsel
Model type: Not specified
Model format: Not specified
Environment: Not specified
This is a set of MATLAB procedures for automated segmentation and counting of macrophages in multiple IHC stained tissue samples. Execution assumes that three aligned single-channel greyscale images of a given tissue area are available, representing IHC stainings with CD14 and CD163 antibodies (targeting macrophages) as well as DAPI staining (targeting cell cores). After detection of evaluation subregion (based on DAPI channel information), IHC stained macrophages will be masked and counted (based ...
Creators: René Hänsel, Marcus Wagner
Submitter: René Hänsel
Model type: Not specified
Model format: Matlab package
Environment: Matlab