The overall goal of this project area is to provide methods to semantically integrate and provide access to relevant data and metadata from selected resources (see projects 1.2 and 1.3). Original data are provided by several epidemiological and clinical trials and competence networks. Providing these data semantically necessitates the integration of raw data and analysis results together with corresponding metadata. Moreover, we will annotate metadata and instances, i.e., create links to other possibly external data resources (e.g. ontologies), and, thus, make data publicly available within the Linked Open Data (LOD) cloud (http://lod-cloud.net) with privacy preservations.