Models & Phenotypes

Claus

The Claus model is a genetic breast cancer risk calculation model assuming a single rare, highly penetrant gene. The extended version of the Claus model (eClaus), as implemented in the commercial pedi...

Hand Grip Strength in Leipzig

We mapped measured hand grip data of the large LIFE Adult population (10,000 participants) onto the Leipzig map. In particular, we locate each participant at the time of participation in Leipzig and, ...

Interactive Pathway Activity Analysis platform

The platform is intended for visualization of expression- and mutation-driven changes in biological pathway activities in cancer datasets available in ICGC. The impact of somatic mutations on protein-...

MMRpredict

"MMRpredict" is a risk prediction model for patients with colorectal cancer (Barnetson et al. 2006). It calculates the risk of having a mutation in the mismatch repair genes MLH1, MSH2 and MSH6 (overa...