Summary of oposSOM analysis results - Pathway signal flow
Pathway signal flow
Pathway signal flow (PSF) algorithm calculates activity of cellular signalling cascades for selected pathways (KEGG database). Reports show an overview about the pathways along with genes contained in data (p.1 in PDF) and sink nodes (p.2). Additionally, the signal strength is visualized for each histological subtype (p.3 ff).
Transcriptome Analytics Browser - Tour (part 4 of 5)
Task III: Functional mining
We applied Pathway Signal Flow (PSF) algorithm to calculate activity of cellular signalling. Importantly, this approach explicitly involves pathway topologies and provides proper visualization of the signal strengths.
Several pathways can be inspected using the select box.
The Leipzig Health Atlas is an alliance of medical ontologists, medical systems biologists and clinical trials groups to design and implement a multi-functional and quality-assured atlas. It provides models, data and metadata on specific use cases from medical research fields.